Endotoxic shock

Known as: gram negative shock, Gram-negative septic shock, Endotoxic septic shock 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Inflammatory caspases, such as caspase-1 and -11, mediate innate immune detection of pathogens. Caspase-11 induces pyroptosis, a… (More)
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Highly Cited
2008
Highly Cited
2008
Caspase-1 serves an essential function in the initiation of inflammation by proteolytically maturing the cytokines interleukin 1… (More)
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Highly Cited
2006
Highly Cited
2006
Septic shock is a leading cause of morbidity and mortality. However, genetic factors predisposing to septic shock are not fully… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Angiopoietin-1 (Ang1) plays an essential role in embryonic vasculature development, protects the adult peripheral… (More)
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Highly Cited
1999
Highly Cited
1999
Poly (ADP-ribose) polymerase-1 is a nuclear DNA-binding protein that participates in the DNA base excision repair pathway in… (More)
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Highly Cited
1999
Highly Cited
1999
The regulation of monocyte function and the inhibition of TNF-alpha production during bacterial sepsis are critical in… (More)
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Highly Cited
1995
Highly Cited
1995
Mice deficient in inducible nitric oxide synthase (iNOS) were generated to test the idea that iNOS defends the host against… (More)
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Highly Cited
1995
Highly Cited
1995
IL-1 beta-converting enzyme (ICE) cleaves pro-IL-1 beta to generate mature IL-1 beta. ICE is homologous to other proteins that… (More)
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Highly Cited
1995
Highly Cited
1995
Previous studies in vivo have shown that IL-10 infusion can prevent lethal endotoxic shock. Mice deficient in the production of… (More)
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Highly Cited
1994
Highly Cited
1994
Antibody neutralization studies have established interferon gamma (IFN-gamma) as a critical mediator of endotoxic shock. The… (More)
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