Elacridar
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Multidrug resistance (MDR) is a complex phenomenon caused by numerous reasons in cancer chemotherapy. It is related to the…
The study objective was to develop a formulation of elacridar to overcome its dissolution-rate-limited bioavailability. Elacridar…
The IGROVCDDP cisplatin-resistant ovarian cancer cell line is also resistant to paclitaxel and models the resistance phenotype of…
PurposePreviously, we studied the effect of co-administration of paclitaxel with the second generation ABCB1 (p-gp) modulator…
PurposeThe selective protein tyrosine kinase inhibitor, imatinib, inhibits the growth of glioma cells in preclinical models, but…
Mefloquine is a chiral neurotoxic antimalarial agent showing stereoselective brain uptake in humans and rats. It is a substrate…