GF 120918

Known as: GF-120918, GF120918, GG 918 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Lapatinib is a tyrosine kinase inhibitor approved for use in combination with capecitabine to treat advanced or metastatic breast… (More)
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2008
2008
Metabolism and transport from intestinal cells back into the lumen by ATP-binding cassette (ABC) transporters is believed to… (More)
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2006
2006
The hepatic excretion of hydrophilic conjugates, end products of phase II metabolism, is not completely understood. In the… (More)
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2006
2006
1. Breast cancer resistance protein (BCRP, ABCG2) is a drug efflux transporter that is believed to affect the drug disposition of… (More)
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Highly Cited
2004
Highly Cited
2004
The breast cancer resistance protein (BCRP/ABCG2) is, like P-glycoprotein (P-gp), a member of the ABC family of drug transporters… (More)
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Highly Cited
2003
Highly Cited
2003
The existence of an ATP-dependent methotrexate (MTX) efflux mechanism has long been postulated; however, until recently, the… (More)
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Highly Cited
2002
Highly Cited
2002
Previously, we have reported that a multidrug-resistant, mitoxantrone (MX)-selected cell line, MCF7/MX, is highly cross-resistant… (More)
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2002
2002
To determine if saquinavir mesylate (saquinavir) is a substrate of human multidrug resistance-associated protein 1 (hMRP1 [ABCC1… (More)
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Highly Cited
2001
Highly Cited
2001
This study was aimed at characterizing the role of BCRP/MXR/ABCP (BCRP) in resistance of the human ovarian tumor cell lines T8… (More)
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Highly Cited
2000
Highly Cited
2000
Purpose. The objectives of this work were to evaluate the importance of moderate passive permeability on apparent P-glycoprotein… (More)
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