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GG918

National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Multidrug-resistant (MDR) cancer may be treated using combinations of encapsulated cytotoxic drugs and chemosensitizers. To… Expand
Highly Cited
2005
Highly Cited
2005
In vitro and animal experiments suggest that P‐glycoprotein forms a functional barrier between maternal and fetal blood… Expand
Review
2004
Review
2004
Drug efflux by intestinal P-glycoprotein (P-gp) is known to decrease the bioavailability of many CYP3A4 substrates. We have… Expand
Highly Cited
2003
Highly Cited
2003
The disposition of tacrolimus and the influence of cyclosporine, troleandomycin, and GF120918 (GG918, or N-[4-[2-(1,2,3,4… Expand
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Highly Cited
2003
Highly Cited
2003
P-Glycoprotein (P-gp) has been hypothesized to modulate intestinal drug metabolism by increasing the exposure of drug to… Expand
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Review
2003
Review
2003
As discussed in earlier articles, predictions of in vivo drug-drug interactions from in vitro studies is a subject of high… Expand
Highly Cited
2003
Highly Cited
2003
GG918, a synthetic inhibitor of P-glycoprotein-mediated mammalian tumour multidrug resistance, was found to be equipotent to… Expand
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Highly Cited
2002
Highly Cited
2002
Drug efflux by intestinal P-glycoprotein (P-gp) is known to decrease the oral bioavailability of many CYP3A4 substrates. We… Expand
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Highly Cited
2000
Highly Cited
2000
The human multidrug transporter MDR1 P-glycoprotein and the multidrug resistance proteins MRP1 and MRP2 transport a range of… Expand
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Highly Cited
1996
Highly Cited
1996
We sought to develop an assay for measuring the inhibition of P-glycoprotein (Pgp) function in whole blood as an indicator of in… Expand
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