GG918

 

Topic mentions per year

Topic mentions per year

1996-2015
024619962015

Papers overview

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2006
2006
Multidrug-resistant (MDR) cancer may be treated using combinations of encapsulated cytotoxic drugs and chemosensitizers. To… (More)
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2006
2006
The effects of hepatic uptake and efflux transporters on erythromycin (ERY) disposition and metabolism were examined by comparing… (More)
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2004
2004
CYP3A4-transfected Caco-2 cells were used as an in vitro system to predict the importance of drug metabolism and transport on… (More)
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2003
2003
The disposition of tacrolimus and the influence of cyclosporine, troleandomycin, and GF120918 (GG918, or N-[4-[2-(1,2,3,4… (More)
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Highly Cited
2003
Highly Cited
2003
GG918, a synthetic inhibitor of P-glycoprotein-mediated mammalian tumour multidrug resistance, was found to be equipotent to… (More)
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Highly Cited
2002
Highly Cited
2002
Drug efflux by intestinal P-glycoprotein (P-gp) is known to decrease the oral bioavailability of many CYP3A4 substrates. We… (More)
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Highly Cited
2000
Highly Cited
2000
The human multidrug transporter MDR1 P-glycoprotein and the multidrug resistance proteins MRP1 and MRP2 transport a range of… (More)
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1999
1999
SummaryThe acridone carboxamide derivative GG918 (N-{4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)-ethyl]-phenyl}-9,10… (More)
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Highly Cited
1999
Highly Cited
1999
It was recently shown that naturally occurring Mdr1a mutant fetuses of the CF-1 outbred mouse stock have no placental Mdr1a P… (More)
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1996
1996
We sought to develop an assay for measuring the inhibition of P-glycoprotein (Pgp) function in whole blood as an indicator of in… (More)
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