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GG918

 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Multidrug-resistant (MDR) cancer may be treated using combinations of encapsulated cytotoxic drugs and chemosensitizers. To… Expand
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Review
2004
Review
2004
Drug efflux by intestinal P-glycoprotein (P-gp) is known to decrease the bioavailability of many CYP3A4 substrates. We have… Expand
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Highly Cited
2004
Highly Cited
2004
AbstractPurpose. To determine whether female sex-steroid hormones and their metabolites can modulate P-glycoprotein (P-gp… Expand
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Highly Cited
2003
Highly Cited
2003
P-Glycoprotein (P-gp) has been hypothesized to modulate intestinal drug metabolism by increasing the exposure of drug to… Expand
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Highly Cited
2003
Highly Cited
2003
GG918, a synthetic inhibitor of P-glycoprotein-mediated mammalian tumour multidrug resistance, was found to be equipotent to… Expand
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2003
2003
The disposition of tacrolimus and the influence of cyclosporine, troleandomycin, and GF120918 (GG918, or N-[4-[2-(1,2,3,4… Expand
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Review
2003
Review
2003
As discussed in earlier articles, predictions of in vivo drug-drug interactions from in vitro studies is a subject of high… Expand
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Highly Cited
2002
Highly Cited
2002
Drug efflux by intestinal P-glycoprotein (P-gp) is known to decrease the oral bioavailability of many CYP3A4 substrates. We… Expand
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Highly Cited
2000
Highly Cited
2000
The human multidrug transporter MDR1 P-glycoprotein and the multidrug resistance proteins MRP1 and MRP2 transport a range of… Expand
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1996
1996
We sought to develop an assay for measuring the inhibition of P-glycoprotein (Pgp) function in whole blood as an indicator of in… Expand
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