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Econazole

Known as: Econazole [Chemical/Ingredient], Ekonazole, 1-(2,4-Dichloro-beta-((P-chlorobenzyl)oxy)phenethyl)imidazole 
An imidazole with antifungal property. Econazole compromises the integrity of fungal cell wall through inhibiting 14-alpha demethylase, which… 
National Institutes of Health

Related topics

Related topics

25 relations

Broader (2)

14-alpha Demethylase InhibitorsAntifungal Agents
AzolesCutaneous CandidiasisEconazole NitrateEconazole Nitrate 10 MG/ML Topical Cream

Narrower (5)

Gyno-Pervaryl 150Gyno-PevarylPevarylPevisone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM
The transient receptor potential vanilloid 5 (TRPV5) channel is a member of the transient receptor potential (TRP) channel family… 
Highly Cited
2012
Highly Cited
2012
Distribution, behavior and fate of azole antifungals during mechanical, biological, and chemical treatments in sewage treatment plants in China.
Review
2005
Review
2005
Antifungal Susceptibilities of Candida Species Causing Vulvovaginitis and Epidemiology of Recurrent Cases
ABSTRACT There are limited data regarding the antifungal susceptibility of yeast causing vulvovaginal candidiasis, since cultures… 
Highly Cited
2004
Highly Cited
2004
Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole
TRPM2 is a Ca2+-permeable non-selective cation channel that uniquely is activated by intracellular ADP-ribose. To date, only one… 
Highly Cited
2001
Highly Cited
2001
Comparison of the chiral resolution of econazole, miconazole, and sulconazole by HPLC using normal-phase amylose CSPs
Abstract Resolution of the enantiomers of (±)-econazole, (±)-miconazole, and (±)-sulconazole has been achieved on different… 
Highly Cited
1999
Highly Cited
1999
Positively and negatively charged submicron emulsions for enhanced topical delivery of antifungal drugs.
Highly Cited
1997
Highly Cited
1997
In‐vitro Permeability of the Human Nail and of a Keratin Membrane from Bovine Hooves: Prediction of the Penetration Rate of Antimycotics through the Nail Plate and their Efficacy
In contrast to the partition coefficient octanol/water the molecular size of penetrating drugs has a noticeable influence on the… 
Highly Cited
1987
Highly Cited
1987
Imidazole antimycotics: Selective inhibitors of steroid aromatization and progesterone hydroxylation
Highly Cited
1985
Highly Cited
1985
Pityrosporum folliculitis: a common disease of the young and middle-aged.
Review
1975
Review
1975
Principles in the management of oculomycosis. XXXI Edward Jackson memorial lecture.
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