Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 227,741,297 papers from all fields of science
Search
Sign In
Create Free Account
14-alpha Demethylase Inhibitors
Known as:
Lanosterol 14 alpha-Demethylase Inhibitors
, Inhibitors, 14alpha-Demethylase
, Inhibitors, 14-alpha Demethylase
Expand
Compounds that specifically inhibit STEROL 14-DEMETHYLASE. A variety of azole-derived ANTIFUNGAL AGENTS act through this mechanism.
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
14 relations
Narrower (10)
Clotrimazole
Econazole
Fluconazole
Itraconazole
Expand
In Blood
aspects of radiation effects
chemical synthesis
standards characteristics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Gene expression and enzyme function of two cytochrome P450 3A isoenzymes in rat and cattle precision cut liver slices
M. Maté
,
M. Ballent
,
K. Larsen
,
A. Lifschitz
,
C. Lanusse
,
G. Virkel
Xenobiotica; the fate of foreign compounds in…
2015
Corpus ID: 26417947
Abstract 1. Precision-cut liver slices are one of the in vitro models used in studies concerning xenobiotic metabolism. Sparse…
Expand
2005
2005
The roles of kupffer cells in hepatic dysfunction induced by ischemia/reperfusion in rats
Joo-Yeon Jung
,
Sun Lee
Archives of pharmacal research
2005
Corpus ID: 25331655
This study examined the role of Kupffer cells in altering the hepatic secretory and microsomal function during ischemia and…
Expand
1998
1998
Effects of a vegetables-fruit mixture on liver and colonic 1,2-dimethylhydrazine-metabolizing enzyme activities in rats fed low- or high-fat diets.
J. M. Rijnkels
,
G. Alink
Cancer Letters
1998
Corpus ID: 27654854
1997
1997
Effects of provitamin A or non-provitamin A carotenoids on liver xenobiotic-metabolizing enzymes in mice.
P. Astorg
,
S. Gradelet
,
J. Leclerc
,
M. Siess
Nutrition and Cancer
1997
Corpus ID: 32678652
To determine whether carotenoids can modulate xenobiotic-metabolizing enzymes in mice, catalytic activities of several phase I…
Expand
1994
1994
Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo.
D. Swinney
,
O. So
,
+6 authors
P. Burton
Biochemistry
1994
Corpus ID: 13208276
The discovery of selective lanosterol 14 alpha-demethylase inhibitors may lead to novel hypolipidemic drugs. RS-21607, (2S,4S…
Expand
1987
1987
In vivo protection by protein A of hepatic microsomal mixed function oxidase system of CCl4-administered rats.
S. Srivastava
,
K. P. Singh
,
A. Saxena
,
P. Seth
,
P. K. Ray
Biochemical Pharmacology
1987
Corpus ID: 21491601
1986
1986
Suppressive effect of interferon inducer, polyriboinosinic acid-polyribocytidylic acid on induction of uridine diphosphate-glucuronyltransferases and monooxygenases in liver microsomes of rats.
T. Matsunaga
,
K. Nagata
,
+4 authors
H. Yoshimura
Journal of Pharmacobio-Dynamics
1986
Corpus ID: 6091361
The effect of polyriboinosinic acid-polyribocytidylic acid [poly(I).poly(C)] on glucuronyltransferase activities toward 4…
Expand
1976
1976
Enhancement of microsomal monooxygenase, epoxide hydrase and UDPglucuronyltransferase by aldrin, dieldrin and isosafrole administrations in rat liver.
H. Vainio
,
M. Parkki
Toxicology
1976
Corpus ID: 4925748
Highly Cited
1973
Highly Cited
1973
Drug hydroxylation and glucuronidation in liver microsomes of phenobarbital-treated rats.
H. Vainio
Xenobiotica; the fate of foreign compounds in…
1973
Corpus ID: 31880922
Abstract1. The rise in p-nitroanisole O-demethylase activity in liver microsomes after phenobarbital treatment of rats slightly…
Expand
1970
1970
Amino acid induction and carbohydrate repression of dimethylnitrosamine demethylase in rat liver.
N. Venkatesan
,
J. Arcos
,
M. Argus
Cancer Research
1970
Corpus ID: 20087353
Starvation of rats for 24 hr considerably enhances hepatic dimethylnitrosamine demethylase activity, and 3-methylcholanthrene…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE