14-alpha Demethylase Inhibitors

Known as: Lanosterol 14 alpha-Demethylase Inhibitors, Inhibitors, 14alpha-Demethylase, Inhibitors, 14-alpha Demethylase 
Compounds that specifically inhibit STEROL 14-DEMETHYLASE. A variety of azole-derived ANTIFUNGAL AGENTS act through this mechanism.
National Institutes of Health

Papers overview

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Review
2014
Review
2014
In 2007, the Ubiquitously Transcribed Tetratricopeptide Repeat on chromosome X (UTX) was identified as a histone demethylase that… (More)
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2014
2014
PURPOSE Ewing sarcoma is a pediatric bone tumor that absolutely relies on the transcriptional activity of the EWS/ETS family of… (More)
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2014
2014
Histone demethylase KDM2A has been reported to be dysregulated in lung cancer. However, its function in gastric cancer remains… (More)
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2010
2010
We previously reported that the cancer drug clinical candidate tipifarnib kills the causative agent of Chagas disease… (More)
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1997
1997
The present study investigated the interactions between cytochrome P450 (P450) enzymes and the NADPH:cytochrome oxidoreductase… (More)
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1994
1994
The discovery of selective lanosterol 14 alpha-demethylase inhibitors may lead to novel hypolipidemic drugs. RS-21607, (2S,4S… (More)
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1990
1990
Studies were conducted to evaluate the possible induction or the maintenance of cytochrome P-450IIE1 in primary hepatocyte… (More)
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1983
1983
The effects of diabetes on the liver microsomal monooxygenase enzymes and carcinogen metabolism have been studied in rats… (More)
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1975
1975
The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on a number of hepatic and extrahepatic foreign-compound-metabolizing… (More)
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