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Itraconazole

Known as: Itraconazol, (+-)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup 2)-1,2,4-triazolin-5-one, Itraconazole [Chemical/Ingredient] 
A synthetic triazole agent with antimycotic properties. Formulated for both topical and systemic use, itraconazole preferentially inhibits fungal… 
National Institutes of Health

Related topics

Related topics

42 relations

Broader (2)

14-alpha Demethylase InhibitorsCytochrome P-450 CYP3A Inhibitors
AIDS-Related Opportunistic InfectionsAntifungal AgentsAstemizoleAzoles

Narrower (5)

OrungalR-51211Sporanoxcyclodextrin itraconazole

Papers overview

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2005
2005
A case of chromoblastomycosis with an unusual clinical manifestation caused by Phialophora verrucosa on an unexposed area: Treatment with a combination of amphotericin B and 5-flucytosine
1999
1999
Itraconazole oral solution for the treatment of tinea capitis using the pulse regimen.
A 7-year-old boy with Trichophyton tonsurans tinea capitis was cured following the administration of itraconazole oral solution… 
1998
1998
Successful treatment of toenail mycosis with terbinafine and itraconazole gives long term benefits
EDITOR —In 1995 we published a study comparing treatments with terbinafine and itraconazole for tinea infection of the toenail.1… 
1997
1997
Primary cutaneous coccidioidomycosis and subsequent drug eruption to itraconazole in a dog.
Three weeks after traveling to Arizona, a 13-month-old, female Labrador retriever developed draining tracts in the right hind… 
Highly Cited
1996
Highly Cited
1996
Peripheral edema due to nifedipine-itraconazole interaction: a case report.
We report a case of a drug interaction observed in a patient who was administered itraconazole for pedal onychomycosis and whose… 
Highly Cited
1995
Highly Cited
1995
Pulse therapy with one-week itraconazole monthly for three or four months in the treatment of onychomycosis.
In an open study, twenty-eight patients with toenail onychomycosis were treated with monthly cycles of 400 mg itraconazole daily… 
1993
1993
Effect of hydroxypropyl-β-cyclodextrin on efficacy of oral itraconazole in disseminated murine cryptococcosis
The therapeutic efficacy of itraconazole solubilized in either the commonly used vehicle, polyethylene-glycol-200 (PEG) or… 
1992
1992
In vitro susceptibility of 245 yeast isolates to amphotericin B, 5-fluorocytosine, ketoconazole, fluconazole and itraconazole.
The in vitro activity of amphotericin B, 5-fluorocytosine, ketoconazole, fluconazole and itraconazole was tested against 245… 
1987
1987
Therapeutic efficacy of itraconazole in systemic candidosis in guinea pigs.
Fifty non-immunocompromised guinea pigs were infected by the intravenous route with 8,000 blastospores of Candida albicans per… 
1984
1984
In vitro and in vivo activities of ketoconazole and itraconazole against Pityrosporum orbiculare
The MICs of ketoconazole and itraconazole against Pityrosporum orbiculare were 0.02 to 0.05 and 0.1 to 0.2 micrograms ml-1…