Fluconazole

Known as: 2,4-Difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol, 2-(2,4-DIFLUOROPHENYL)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-ol, Fluconazolum 
A synthetic triazole with antifungal activity. Fluconazole preferentially inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1946-2017
020040060019462016

Papers overview

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Highly Cited
2007
Highly Cited
2007
BACKGROUND Patients with neutropenia resulting from chemotherapy for acute myelogenous leukemia or the myelodysplastic syndrome… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Invasive fungal infections are an important cause of morbidity and mortality after allogeneic hematopoietic stem-cell… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Anidulafungin, a new echinocandin, has potent activity against candida species. We compared anidulafungin with… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Inadequate antimicrobial treatment is an independent determinant of hospital mortality, and fungal bloodstream… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND No safe and convenient regimen has proved to be effective for the management of recurrent vulvovaginal candidiasis… (More)
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Highly Cited
2000
Highly Cited
2000
Two randomized, placebo-controlled trials previously showed that fluconazole (400 mg/d) administered prophylactically decreases… (More)
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Highly Cited
1995
Highly Cited
1995
A randomized, double-blind, placebo-controlled trial assessed the efficacy and toxicity of 400 mg/day fluconazole in preventing… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND Amphotericin B has long been the standard treatment for candidemia, but its use is complicated by its toxicity. More… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND AND METHODS Superficial and systemic fungal infections are a major problem among severely immunocompromised patients… (More)
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Highly Cited
1991
Highly Cited
1991
BACKGROUND In early 1990 fluconazole was introduced as a prophylactic antifungal agent after bone marrow transplantation. During… (More)
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