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Fluconazole

Known as: 2,4-Difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol, 2-(2,4-DIFLUOROPHENYL)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-ol, Fluconazolum 
A synthetic triazole with antifungal activity. Fluconazole preferentially inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting… 
National Institutes of Health

Related topics

Related topics

42 relations

Broader (3)

14-alpha Demethylase InhibitorsCytochrome P-450 CYP2C9 InhibitorsTriazoles
200 ML Fluconazole 2 MG/ML InjectionAntifungal AgentsAstemizoleAzoles

Narrower (9)

BiozoleBéagyneDiflucanFluc Hexal

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Antifúngicos: mecanismo de acción en células de levaduras
Las micosis, especialmente las invasoras, se han convertido en un importante problema de salud al aumentar espectacularmente su… 
Highly Cited
2006
Highly Cited
2006
Antifungal susceptibility of epigallocatechin 3-O-gallate (EGCg) on clinical isolates of pathogenic yeasts.
Highly Cited
2001
Highly Cited
2001
Antifungal triazoles induce malformations in vitro.
Highly Cited
2001
Highly Cited
2001
Trichosporon species infection in bone marrow transplanted patients.
Highly Cited
2000
Highly Cited
2000
Biochemical characterization and subcellular localization of the sterol C‐24(28) reductase, Erg4p, from the yeast Saccharomyces cerevisiae
Highly Cited
1999
Highly Cited
1999
Prophylactic antibiotics in patients undergoing laser resurfacing of the skin.
Highly Cited
1998
Highly Cited
1998
A fourth gene from the Candida albicans CDR family of ABC transporters.
Highly Cited
1995
Highly Cited
1995
Isolation of fluconazole-resistant Candida albicans from human immunodeficiency virus-negative patients never treated with azoles.
Isolation of fluconazole-resistant strains of Candida species from human immunodeficiency virus (HIV)-infected patients after… 
Highly Cited
1994
Highly Cited
1994
Access to therapy in the Multicenter AIDS Cohort Study, 1989-1992.
Highly Cited
1988
Highly Cited
1988
A prospective study of the efficacy of fluconazole (UK-49,858) against deep-seated fungal infections.
Fluconazole (UK-49,858) is a new bis-triazole antifungal drug that can be administered both orally and intravenously. We… 
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