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Econazole Nitrate

Known as: 1-[2-{(4-chloro-phenyl)methoxy}-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole Mononitrate, Nitrate, Econazole, nitrate econazole 
An imidazole derivative and broad-spectrum antimycotic agent with fungistatic properties. Econazole nitrate inhibits biosynthesis of ergosterol… 
National Institutes of Health

Related topics

Related topics

11 relations
Antifungal AgentsAzolesCutaneous CandidiasisEconazole Nitrate 10 MG/ML Topical Cream

Broader (1)

Econazole

Narrower (2)

Gyno-Pervaryl 150Pevaryl

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Skin permeation of econazole nitrate formulated in an enhanced hydrophilic multiple emulsion
Local delivery of imidazolic antifungals is limited by its extreme lipophilicity. Multiple emulsions (ME) are a potential vehicle… 
2016
2016
Novel Citric Acid Dendritic Hydrogels for the Delivery of Econazole Nitrate and its Antifungal Activity
Article history: Received on: 01/09/2016 Revised on: 17/10/2016 Accepted on: 04/11/2016 Available online: 28/12/2016 Econazole is… 
2014
2014
Econazole Nitrate Induces Apoptosis in MCF-7 Cells via Mitochondrial and Caspase Pathways
Econazole nitrate (EN), a synthetic compound, is now in use as a routine antifungal drug. EN was shown to have antitumor effect… 
2008
2008
Use of Natural Polysaccharides in Medical Textile Applications
In this thesis chitosan and s-cyclodextrin were used as candidates in medical textile applications. The antimicrobial activity of… 
1996
1996
Imidazole antifungals Miconazole and Econazole induce apoptosis in mouse lymphoma and human T cell leukemia cells: regulation by Bcl-2 and potential role of calcium.
We have recently reported that thapsigargin (TG), a specific endoplasmic reticulum (ER)-associated Ca(2+)-ATPase inhibitor… 
Review
1993
Review
1993
The detection and assessment of the aneugenic potential of environmental chemicals: the European Community Aneuploidy Project.
1983
1983
Double-blind comparison of the efficacy, toleration and safety of tioconazole base 1% and econazole nitrate 1% creams in the treatment of patients with fungal infections of the skin or erythrasma.
A total of 61 patients with proven fungal infection of the skin or with erythrasma took part in a double-blind comparison of the… 
1979
1979
Freeze-fracture studies of the plasmalemma of Candida albicans after treatment with econazole-nitrate.
In electron microscopic studies the interior of the plasmalemma of Candida albicans was revealed by means of the freeze-fracture… 
1976
1976
Absorption and disposition of econazole nitrate after application to the skins and vaginas of rabbits.
1. The absorption and tissue distribution of radioactivity has been studied in rabbits after application of a cream containing 10… 
1976
1976
Interactions between econazole, a broad-spectrum antimicrobic substance, and topically active glucocorticoids.
Econazole is a broad-spectrum antimicrobic substance which acts by permeabilizing the cell membranes. Glucocorticoids by their… 
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