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EIF2AK1 gene

Known as: EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 1, heme regulated initiation factor 2 alpha kinase, EIF2AK1 
This gene plays a role in the negative regulation of protein synthesis.
National Institutes of Health

Related topics

Related topics

11 relations
EIF2AK2 geneEIF2AK3 geneEukaryotic Translation Initiation Factor 2-Alpha Kinase 1PRKR gene

Narrower (1)

EIF2AK2 wt Allele

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Recombinant PTD-Cu/Zn SOD attenuates hypoxia–reoxygenation injury in cardiomyocytes
Abstract Background. Oxidative stress plays a pivotal role in myocardial ischemia–reperfusion injury. Increasing the protein… 
Highly Cited
2002
Highly Cited
2002
Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase.
The maturation and activation of newly synthesized molecules of the heme-regulated inhibitor of protein synthesis (HRI) in… 
Review
1996
Review
1996
Postdischarge utilization of medical services by high-risk infants: experience in a large managed care organization.
BACKGROUND Infants discharged from intensive care nurseries are a high-risk infant (HRI) population known to have increased… 
1992
1992
Effects of hemin and porphyrin compounds on intersubunit disulfide formation of heme-regulated eIF-2 alpha kinase and the regulation of protein synthesis in reticulocyte lysates.
To study the mechanism by which heme regulates the heme-regulated eIF-2 alpha kinase (HRI), the effects of various protoporphyrin… 
1991
1991
Tissue distribution and immunoreactivity of heme-regulated eIF-2 alpha kinase determined by monoclonal antibodies.
A highly purified preparation of heme-regulated inhibitor (HRI), an eIF-2 alpha kinase, from rabbit reticulocyte lysates has been… 
1989
1989
Disulfide bond formation in the regulation of eIF-2 alpha kinase by heme.
The inhibition of the autophosphorylation of the heme-regulated eukaryotic initiation factor (eIF)-2 alpha kinase (HRI) by hemin… 
Highly Cited
1987
Highly Cited
1987
Nucleotide sequence analysis of RepFIC, a basic replicon present in IncFI plasmids P307 and F, and its relation to the RepA replicon of IncFII plasmids
RepFIC is a basic replicon of IncFI plasmid P307 which is located within a 3.09-kilobase SmaI fragment. The nucleotide sequence… 
Review
1980
Review
1980
Isolation of a translational inhibitor from wheat germ with protein kinase activity that phosphorylates initiation factor eIF-2.
Highly Cited
1979
Highly Cited
1979
Regulation of protein synthesis in rabbit reticulocyte lysates: additional initiation factor required for formation of ternary complex (eIF-2.GTP.Met-tRNAf) and demonstration of inhibitory effect of…
Heme deficiency in rabbit reticulocytes and their lysates leads to the activation of a heme-regulated translational inhibitor… 
1979
1979
Regulation of protein synthesis in rabbit reticulocyte lysates: the hemeregulated protein kinase (HRI) and double stranded RNA induced protein kinase (dRI) phosphorylate the same site(s) on…
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