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PRKR gene

Known as: EIF2AK2, EIF2AK2 Gene, Eukaryotic Translation Initiation Factor 2-Alpha Kinase 2 Gene 
This gene plays a role in the negative regulation of protein synthesis.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Purpose: Sjögren’s syndrome (SS) is an autoimmune disease characterized by dry mouth and eyes. To date, the exact molecular… 
Highly Cited
2016
Highly Cited
2016
Sepsis, severe sepsis and septic shock are the main cause of mortality in non-cardiac intensive care units. Immunometabolism has… 
Highly Cited
2016
Highly Cited
2016
A primary insult to the pancreatic islets of Langerhans, leading to the activation of innate immunity, has been suggested as an… 
Review
2015
Review
2015
Autophagy is an evolutionarily conserved process in eukaryotes that eliminates harmful components and maintains cellular… 
Highly Cited
2015
Highly Cited
2015
Human olfactory neurosphere-derived (ONS) cells have the potential to provide novel insights into the cellular pathology of… 
Highly Cited
2013
Highly Cited
2013
A chemical screen designed to identify novel inducers of autophagy led to the discovery that signal transducer and activator of… 
Highly Cited
2012
Highly Cited
2012
The inflammasome regulates the release of caspase activation-dependent cytokines, including interleukin (IL)-1β, IL-18 and high… 
2011
2011
IntroductionThe objective of this study is to determine if multiple systemic autoimmune diseases (SAID) share gene expression… 
Highly Cited
2008
Highly Cited
2008
Protein kinase PKR (also known as EIF2AK2) is activated during viral infection and phosphorylates the α subunit of eukaryotic…