Atlas of Genetics and Cytogenetics in Oncology and Haematology EIF 2 AK 2 ( eukaryotic translation initiation factor 2-alpha kinase 2 )

@inproceedings{Blalock2012AtlasOG,
  title={Atlas of Genetics and Cytogenetics in Oncology and Haematology EIF 2 AK 2 ( eukaryotic translation initiation factor 2-alpha kinase 2 )},
  author={William Blalock and Lucio Cocco},
  year={2012}
}
Key Promoter Elements: TATA-less (No TATA Box). 1. KCS (Kinase Conserved Sequence): Nucleotides 67 to -81 from the transcriptional start site. Required for basal expression utilizing Sp factors. Al o required in combination with the ISRE for interfero nstimulated expression (Kuhen and Samuel, 1997; Kuhen et al., 1998; Kuhen and Samuel, 1999; Ward and Samuel, 2002). 2. ISRE (Interferon-stimulated response element): Nucleotides -50 to -62 from the transcriptional sta rt site. Required for the… CONTINUE READING

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