EIF2AK3 gene

Known as: PEK, PERK, eukaryotic translation initiation factor 2 alpha kinase 3 
This gene plays a role in the regulation of translation.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Tumor hypoxia is a common microenvironmental factor that adversely influences tumor phenotype and treatment response. Cellular… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in PERK (EIF2AK3) result in permanent neonatal diabetes as well as several other anomalies that underlie the human… (More)
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Review
2006
Review
2006
In response to environmental stresses, a family of protein kinases phosphorylate eIF2 (eukaryotic initiation factor 2) to… (More)
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Highly Cited
2005
Highly Cited
2005
The unfolded protein response (UPR) is an adaptive signaling pathway utilized to sense and alleviate the stress of protein… (More)
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Highly Cited
2004
Highly Cited
2004
Wolcott-Rallison syndrome (WRS) is a rare autosomal-recessive disorder characterized by the association of permanent neonatal or… (More)
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Highly Cited
2004
Highly Cited
2004
In response to environmental stress, cells induce a program of gene expression designed to remedy cellular damage or… (More)
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Highly Cited
2002
Highly Cited
2002
Phosphorylation of eukaryotic initiation factor-2 (eIF2) by pancreatic eIF2 kinase (PEK), induces a program of translational… (More)
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Highly Cited
2000
Highly Cited
2000
Wolcott-Rallison syndrome (WRS) is a rare, autosomal recessive disorder characterized by permanent neonatal or early infancy… (More)
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Highly Cited
2000
Highly Cited
2000
In response to different cellular stresses, a family of protein kinases regulates translation by phosphorylation of the alpha… (More)
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Highly Cited
1998
Highly Cited
1998
In response to various environmental stresses, eukaryotic cells down-regulate protein synthesis by phosphorylation of the alpha… (More)
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