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E2F1 wt Allele

Known as: E2F Transcription Factor 1 wt Allele, RBP3, RBAP1 
Human E2F1 wild-type allele is located in the vicinity of 20q11.2 and is approximately 11 kb in length. This allele, which encodes transcription… 
National Institutes of Health

Related topics

Related topics

14 relations
20q11.2ApoptosisCell CycleE2F1 Degradation Pathway

Broader (1)

E2F1 gene

Papers overview

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2018
2018
microRNA‐136 inhibits proliferation and promotes apoptosis and radiosensitivity of cervical carcinoma through the NF‐&kgr;B pathway by targeting E2F1
Highly Cited
2016
Highly Cited
2016
The long noncoding RNA H19 promotes cell proliferation via E2F-1 in pancreatic ductal adenocarcinoma
ABSTRACT H19 is a long noncoding RNA differentially expressed in many tumors and participates in tumorigenesis. This study aimed… 
Highly Cited
2006
Highly Cited
2006
E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts
Deregulation of the Rb/E2F pathway in human fibroblasts results in an E2F1-mediated apoptosis dependent on Atm, Nbs1, Chk2 and… 
Highly Cited
2002
Highly Cited
2002
An E2F-responsive replication-selective adenovirus targeted to the defective cell cycle in cancer cells: potent antitumoral efficacy but no toxicity to normal cell.
To improve the transduction and distribution of adenovirus in a tumor mass, we generated an adenovirus to selectively replicate… 
Highly Cited
2001
Highly Cited
2001
Attenuation of neurotoxicity in cortical cultures and hippocampal slices from E2F1 knockout mice
The E2F1 transcription factor modulates neuronal apoptosis induced by staurosporine, DNA damage and β‐amyloid. We demonstrate… 
Review
1999
Review
1999
pRb and E2f-1 in mouse development and tumorigenesis.
Highly Cited
1997
Highly Cited
1997
Distinct mechanisms of nuclear accumulation regulate the functional consequence of E2F transcription factors.
Transcription factor E2F plays an important role in coordinating and integrating early cell cycle progression with the… 
Highly Cited
1996
Highly Cited
1996
The CBP co-activator stimulates E2F1/DP1 activity.
The cell cycle-regulating transcription factors E2F1/DP1 activate genes whose products are required for S phase progression… 
Highly Cited
1996
Highly Cited
1996
Use of Normal and Transgenic Mice to Examine the Relationship between Terminal Differentiation of Intestinal Epithelial Cells and Accumulation of Their Cell Cycle Regulators*
A spatially well organized continuum of proliferation, differentiation, and death is displayed along crypt-villus units in the… 
Highly Cited
1995
Highly Cited
1995
Inhibition of in vitro myogenic differentiation by cellular transcription factor E2F1.
Terminal differentiation of cultured myocytes requires withdrawal of the cells from the cell cycle. Constitutive overexpression… 
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