Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

E2F1 gene

Known as: E2F Transcription Factor 1 Gene, RBP3, E2F TRANSCRIPTION FACTOR 1 
This gene plays a regulatory role in G1/S cell cycle checkpoints and apoptosis.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
The 10q26 locus in the second intron of FGFR2 is the locus most strongly associated with estrogen-receptor-positive breast cancer… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 3
Is this relevant?
Highly Cited
2010
Highly Cited
2010
E2F1 is a positive regulator of cell cycle progression and also a potent inducer of apoptosis, especially when activated by DNA… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2010
Highly Cited
2010
microRNAs (miRNAs) play vital roles in several biological processes, including apoptosis, by negatively regulating the expression… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
In the established model of mammalian cell cycle control, the retinoblastoma protein (Rb) functions to restrict cells from… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
The retinoblastoma pathway is often inactivated in human tumors resulting in deregulated E2F activity that can induce both… Expand
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
E2F transcription factors are key regulators of cell proliferation that are inhibited by pRb family tumor suppressors. pRb… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Inhibitors of histone deacetylases (HDACIs) are a new generation of anticancer agents that selectively kill tumor cells. However… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The retinoblastoma protein (Rb)/E2F pathway links cellular proliferation control to apoptosis and is critical for normal… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The p16/RB/E2F regulatory pathway, which controls transit through the G1 restriction point of the cell cycle, is one of the most… Expand
  • figure 1
  • table 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Although a number of transfection experiments have suggested potential targets for the action of the E2F1 transcription factor… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?