Diphtheria Toxin

Known as: Corynebacterium diphtheriae toxin, Diphtheria Toxin [Chemical/Ingredient], Toxin, Corynebacterium Diphtheriae 
An ADP-ribosylating polypeptide produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Transgenic mice expressing the diphtheria toxin receptor (DTR) in specific cell types are key tools for functional studies in… (More)
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Highly Cited
2005
Highly Cited
2005
A new system for lineage ablation is based on transgenic expression of a diphtheria toxin receptor (DTR) in mouse cells and… (More)
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Highly Cited
2005
Highly Cited
2005
Glomerular injury and proteinuria in diabetes (types 1 and 2) and IgA nephropathy is related to the degree of podocyte depletion… (More)
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Highly Cited
2005
Highly Cited
2005
Hypothalamic neurons that express neuropeptide Y (NPY) and agouti-related protein (AgRP) are thought to be critical regulators of… (More)
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Highly Cited
2001
Highly Cited
2001
Specific cell ablation is a useful method for analyzing the in vivo function of cells. We have developed a simple and sensitive… (More)
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Highly Cited
1993
Highly Cited
1993
In producing mutant mice by gene targeting in embryonic stem (ES) cells, the efficient isolation of the homologous recombinants… (More)
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Highly Cited
1992
Highly Cited
1992
The crystal structure of the diphtheria toxin dimer at 2.5 Å resolution reveals a Y-shaped molecule of three domains. The… (More)
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Highly Cited
1992
Highly Cited
1992
A monkey cDNA (pDTS) encoding a diphtheria toxin (DT) sensitivity determinant was isolated by expression cloning in mouse L-M… (More)
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Highly Cited
1980
Highly Cited
1980
At neutral pH, NH4Cl and chloroquine protected cells against diphtheria toxin. A brief exposure of the cells to low pH (4.5-5.5… (More)
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Highly Cited
1978
Highly Cited
1978
Erythrocyte ghosts containing a known number of molecules of purified fragment A of diphtheria toxin with a constant amount of… (More)
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