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Diphtheria Toxin

Known as: Corynebacterium diphtheriae toxin, Diphtheria Toxin [Chemical/Ingredient], Toxin, Corynebacterium Diphtheriae 
An ADP-ribosylating polypeptide produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two… 
National Institutes of Health

Related topics

Related topics

31 relations
2 ML denileukin diftitox 0.15 MG/ML InjectionCorynebacterium diphtheriaeCorynebacterium diphtheriae toxin Ab.IgG:ACnc:Pt:Ser:QnCorynebacterium diphtheriae toxin Ab:ACnc:Pt:Ser:Qn

Broader (4)

Bacterial ToxinsBacterial exotoxinExotoxinsPoisons

Narrower (11)

CRM 107DAB(389)-interleukin 2DAB(389)-interleukin 4DAB(486)-interleukin 2

Papers overview

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Highly Cited
1996
Highly Cited
1996
Organization of Diphtheria Toxin T Domain in Bilayers: A Site-Directed Spin Labeling Study
The diphtheria toxin transmembrane (T) domain was spin-labeled at consecutive residues in a helical segment, TH9. After binding… 
Highly Cited
1995
Highly Cited
1995
Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites
Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the EGF family of growth factors, which… 
Highly Cited
1992
Highly Cited
1992
The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from vero cells is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on…
Diphtheria toxin (DT) receptor associates with a 27-kD membrane protein (DRAP27) in monkey Vero cells. A cDNA encoding DRAP27 was… 
Highly Cited
1992
Highly Cited
1992
Diphtheria toxin- and Pseudomonas A toxin-mediated apoptosis. ADP ribosylation of elongation factor-2 is required for DNA fragmentation and cell lysis and synergy with tumor necrosis factor-alpha.
We have reported that diphtheria toxin (DTX) mediates target cell lysis and intranucleosomal DNA fragmentation (apoptosis) and… 
Review
1989
Review
1989
Regulation of nitrogenase activity by reversible ADP ribosylation.
Highly Cited
1984
Highly Cited
1984
NAD binding site of diphtheria toxin: identification of a residue within the nicotinamide subsite by photochemical modification with NAD.
We showed earlier that exposing mixtures of NAD and diphtheria toxin fragment A to ultraviolet radiation (253.7 nm) induced the… 
Highly Cited
1983
Highly Cited
1983
Antibody Responses to Haemophilus influenzae Type b and Diphtheria Toxin Induced by Conjugates of Oligosaccharides of the Type b Capsule with the Nontoxic Protein CRM197
Oligosaccharides were made from Haemophilus influenzae type b capsular polysaccharide and conjugated to CRM197 by reductive… 
Highly Cited
1983
Highly Cited
1983
Quantitative assessments of IgG and IgE antibodies to inhalant allergens in patients with atopic dermatitis.
Highly Cited
1978
Highly Cited
1978
Association of diphtheria toxin with Vero cells. Demonstration of a receptor.
The interaction of radiolabeled diphtheria toxin with highly sensitive mammalian cell lines was studied. Toxin bound to (or was… 
Highly Cited
1971
Highly Cited
1971
Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule.
Abstract Most preparations of diphtheria toxin that we have examined consist predominantly of mixtures in various proportions of… 
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