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Diphtheria Toxin

Known as: Corynebacterium diphtheriae toxin, Diphtheria Toxin [Chemical/Ingredient], Toxin, Corynebacterium Diphtheriae 
An ADP-ribosylating polypeptide produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two… 
National Institutes of Health

Related topics

Related topics

31 relations
2 ML denileukin diftitox 0.15 MG/ML InjectionCorynebacterium diphtheriaeCorynebacterium diphtheriae toxin Ab.IgG:ACnc:Pt:Ser:QnCorynebacterium diphtheriae toxin Ab:ACnc:Pt:Ser:Qn

Broader (4)

Bacterial ToxinsBacterial exotoxinExotoxinsPoisons

Narrower (11)

CRM 107DAB(389)-interleukin 2DAB(389)-interleukin 4DAB(486)-interleukin 2

Papers overview

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Highly Cited
2000
Highly Cited
2000
Topography of Diphtheria Toxin's T Domain in the Open Channel State
When diphtheria toxin encounters a low pH environment, the channel-forming T domain undergoes a poorly understood conformational… 
Highly Cited
1996
Highly Cited
1996
Organization of Diphtheria Toxin T Domain in Bilayers: A Site-Directed Spin Labeling Study
The diphtheria toxin transmembrane (T) domain was spin-labeled at consecutive residues in a helical segment, TH9. After binding… 
Highly Cited
1991
Highly Cited
1991
A Brassica S-locus gene promoter targets toxic gene expression and cell death to the pistil and pollen of transgenic Nicotiana.
Highly Cited
1989
Highly Cited
1989
Second cytotoxic pathway of diphtheria toxin suggested by nuclease activity.
Diphtheria toxin (DTx) provokes extensive internucleosomal degradation of DNA before cell lysis. The possibility that DNA… 
Highly Cited
1987
Highly Cited
1987
Cytotoxicity of diphtheria toxin A fragment to toxin-resistant murine cells delivered by pH-sensitive immunoliposomes.
pH-sensitive immunoliposomes composed of dioleoylphosphatidylethanolamine and oleic acid (8:2 molar ratio) mediated the delivery… 
Highly Cited
1985
Highly Cited
1985
Diphtheria toxin-resistant mutants of Saccharomyces cerevisiae
We developed a selection procedure based on the observation that diphtheria toxin kills spheroplasts of Saccharomyces cerevisiae… 
Highly Cited
1985
Highly Cited
1985
Photoaffinity labeling of diphtheria toxin fragment A with NAD: structure of the photoproduct at position 148.
Irradiation of mixtures of diphtheria toxin fragment A and [carbonyl-14C]NAD with UV light (253.7 nm) is known to induce… 
Highly Cited
1984
Highly Cited
1984
In vitro biosynthesis of diphthamide, studied with mutant Chinese hamster ovary cells resistant to diphtheria toxin
Diphthamide, a unique amino acid, is a post-translational derivative of histidine that exists in protein synthesis elongation… 
Highly Cited
1980
Highly Cited
1980
Genetic markers for quantitative mutagenesis studies in Chinese hamster ovary cells: characteristics of some recently developed selective systems.
Highly Cited
1980
Highly Cited
1980
Specific disruption of vimentin filament organization in monkey kidney CV-1 cells by diphtheria toxin, exotoxin A, and cycloheximide.
We have examined the effect of diphtheria toxin, Pseudomonas aeruginosa exotoxin A, and cycloheximide on the CV-1 cell… 
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