The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from vero cells is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin- sensitive cells

@article{Mitamura1992The2D,
  title={The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from vero cells is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin- sensitive cells},
  author={Tokushiro Mitamura and Rick Iwamoto and Toshiyuki Umata and Tetsuya Yomo and Itaru Urabe and Makoto Tsuneoka and Eisuke Mekada},
  journal={The Journal of Cell Biology},
  year={1992},
  volume={118},
  pages={1389 - 1399}
}
Diphtheria toxin (DT) receptor associates with a 27-kD membrane protein (DRAP27) in monkey Vero cells. A cDNA encoding DRAP27 was isolated, and its nucleotide sequence was determined. The deduced amino acid sequence revealed that DRAP27 is the monkey homologue of human CD9 antigen. DRAP27 is recognized by CD9 antibodies. A human-mouse hybrid cell line (3279-10) possessing human chromosome 5, sensitive to DT, but not expressing CD9 antigen, was used for transfection experiments with DRAP27. When… CONTINUE READING
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Purification of diphtheria toxin receptor from Veto ceils

  • E. Mekada, H. Senoh, R. lwamoto, Y. Okada, T. Uchida
  • J. Biol
  • 1991
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