FAQ

Dihydroxydihydrobenzopyrenes

Known as: Benzopyrene Dihydrodiols, Dihydrobenzopyrene Diols, Dihydrodiolbenzopyrenes 
Benzopyrenes saturated in any two adjacent positions and substituted with two hydroxyl groups in any position. The majority of these compounds have… (More)
National Institutes of Health

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1952-2017
010203019522016

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In Bloodagonistsantagonists & inhibitorschemical synthesis
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benzo(a)pyrene 7,8-dihydrodiol

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Dihydroxydihydrobenzopyrenes
In Blood
chemical synthesis
standards characteristics
benzo(a)pyrene 7,8-dihydrodiol
antagonists & inhibitors

Papers overview

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Highly Cited
2010
Highly Cited
2010
Lower-defect graphene oxide nanoribbons from multiwalled carbon nanotubes.
An improved method is described for the production of graphene oxide nanoribbons (GONRs) via longitudinal unzipping of… (More)
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2009
2009
Epoxyeicosanoids as mediators of neurogenic vasodilation in cerebral vessels.
Epoxyeicosatrienoic acids (EETs) are potent vasodilators produced from arachidonic acid by cytochrome P-450 (CYP) epoxygenases… (More)
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2006
2006
Inhibition of human cytochrome P450 1A1-, 1A2-, and 1B1-mediated activation of procarcinogens to genotoxic metabolites by polycyclic aromatic hydrocarbons.
Many chemicals in the environment can cause cancer, and polycyclic aromatic hydrocarbons (PAHs) are among the most ubiquitous… (More)
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Highly Cited
2003
Highly Cited
2003
Polymorphisms in human soluble epoxide hydrolase.
Human soluble epoxide hydrolase (hsEH) metabolizes a variety of epoxides to the corresponding vicinal diols. Arachidonic and… (More)
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Highly Cited
1999
Highly Cited
1999
Catalytic asymmetric dihydroxylation of alkenes induced by polymeric chiral ligands
Chiral monomers, bearing different quinidine derivatives, were copolymerized with achiral monomers, producing insoluble… (More)
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1994
1994
Identification of 1-hydroxypyrene glucuronide as a major pyrene metabolite in human urine by synchronous fluorescence spectroscopy and gas chromatography-mass spectrometry.
Humans are exposed to polycyclic aromatic hydrocarbons (PAHs) from various occupational, environmental, medicinal and dietary… (More)
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1993
1993
Metabolism of arachidonic acid to epoxyeicosatrienoic acids, hydroxyeicosatetraenoic acids, and prostaglandins in cultured rat hippocampal astrocytes.
We have recently shown that brain slices are capable of metabolizing arachidonic acid by the epoxygenase pathway. The purpose of… (More)
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1991
1991
Comparative dose-response tumorigenicity studies of dibenzo[alpha,l]pyrene versus 7,12-dimethylbenz[alpha]anthracene, benzo[alpha]pyrene and two dibenzo[alpha,l]pyrene dihydrodiols in mouse skin and…
Comparative studies were conducted of the tumor-initiating activity in mouse skin and carcinogenicity in rat mammary gland of… (More)
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Highly Cited
1983
Highly Cited
1983
The reaction of arachidonic acid epoxides (epoxyeicosatrienoic acids) with a cytosolic epoxide hydrolase.
Epoxyeicosatrienoic acids, formed during the cytochrome P-450-catalyzed oxidation of arachidonic acid, react with a liver… (More)
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1975
1975
Oxidation of the carcinogens benzo [a] pyrene and benzo [a] anthracene to dihydrodiols by a bacterium.
A mutant strain of Beijerinckia, after growth with succinate plus biphenyl, contains an enzyme system that oxidizes benzo [a… (More)
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