Digitonin

Known as: Digitin, Digitonin [Chemical/Ingredient], beta-D-Galactopyranoside, (2alpha,3beta,5alpha,15beta,25R)-2,15-dihydroxyspirostan-3-yl) O-beta-D-glucopyranosyl-(1-3)-O-beta-D-galactopyranosyl-(1-2)-O-(beta-D-xylopyranosyl-(1-3))-O-beta-D-glucopyranosyl-(1-4 
A glycoside obtained from Digitalis purpurea; the aglycone is digitogenin which is bound to five sugars. Digitonin solubilizes lipids, especially in… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Analysis of mitochondrial function is central to the study of intracellular energy metabolism, mechanisms of cell death and… (More)
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Highly Cited
2006
Highly Cited
2006
Alzheimer's disease (AD) is a complex, neurodegenerative disease characterized by the impairment of cognitive function in elderly… (More)
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Review
2001
Review
2001
The desire to take medicines is one feature which distinguishes man, the animal, from his fellow creatures (1). Thus did William… (More)
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Highly Cited
2001
Highly Cited
2001
It has been generally accepted that superoxide anion generated by the mitochondrial respiratory transport chain are vectorially… (More)
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Highly Cited
1999
Highly Cited
1999
The occurrence and the mode of opening of the mitochondrial permeability transition pore (MTP) were investigated directly in… (More)
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Highly Cited
1994
Highly Cited
1994
Caveolae or noncoated plasmalemmal vesicles found in a variety of cells have been implicated in a number of important cellular… (More)
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Highly Cited
1992
Highly Cited
1992
The glycoside digitonin was used to selectively permeabilize the plasma membrane exposing functionally and morphologically intact… (More)
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Highly Cited
1990
Highly Cited
1990
We have developed an in vitro system involving digitonin-permeabilized vertebrate cells to study biochemical events in the… (More)
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Highly Cited
1989
Highly Cited
1989
DUCHENNE muscular dystrophy (DMD) is caused by a defective gene found on the X-chromosome1. Dystrophin is encoded by the DMD gene… (More)
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Highly Cited
1978
Highly Cited
1978
Stimulation of guinea pig granolocytes by digitonin results in superoxide (O-2) generation. A continuous assay shows that there… (More)
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