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Dicumarol
Known as:
Bis(4-hydroxycoumarin-3-yl)methane
, 2H-1-Benzopyran-2-one, 3,3'-methylenebis(4-hydroxy)-
, bis-hydroxycoumarin
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An oral anticoagulant that interferes with the metabolism of vitamin K. It is also used in biochemical experiments as an inhibitor of reductases.
National Institutes of Health
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Related topics
Related topics
44 relations
Alcoholic Intoxication, Chronic
Aneurysm
Ascorbic Acid Deficiency
Bacterial Endocarditis
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Broader (3)
Anticoagulants
Enzyme Inhibitors
Uncoupling Agents
Narrower (2)
Dicoumarin
azodicoumarol
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Problems encountered in long-term treatment with anticoagulants.
S. Husted
,
F. Andreasen
Acta Medica Scandinavica
2009
Corpus ID: 30581717
The course of long-term anticoagulant therapy in 114 out-patients has been evaluated over a three-month period. The evaluation…
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1977
1977
The influence of age on the response to anticoagulants.
S. Husted
,
F. Andreasen
British Journal of Clinical Pharmacology
1977
Corpus ID: 42277382
1 A group of 114 patients on long-term anticoagulant therapy was studied. The daily maintenance dose of both phenprocoumon…
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1973
1973
The nature of the heterogeneity of prothrombin during dicoumarol therapy.
S. Morrison
,
M. Esnouf
Nature: New biology
1973
Corpus ID: 13070567
THE effect of the dicoumarol drugs on clotting factor biosynthesis is similar to that of vitamin K deficiency, in that the…
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Highly Cited
1968
Highly Cited
1968
Comparative pharmacokinetics of coumarin anticoagulants. I. Unusual interaction of bishydroxycoumarin with plasma proteins--development of a new assay.
R. Nagashima
,
G. Levy
,
E. Nelson
Journal of Pharmacy and Science
1968
Corpus ID: 39650827
A widely used method for the determination of bishydroxycoumarin (BHC) in plasma, which involves extraction of BHC from acidified…
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1962
1962
The relationship of subdural hematoma to anticoagulant therapy.
L. M. Wiener
,
M. Nathanson
Transactions of the American Neurological…
1962
Corpus ID: 13411773
At the present time, hypoprothrombinemia induced by anticoagulant drugs is the most commonly encountered coagulation defect in…
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1957
1957
The effect of long term treatment with dicoumarol in myocardial infarction; a controlled clinical study.
Bjerkelund Cj
1957
Corpus ID: 77130121
Highly Cited
1954
Highly Cited
1954
Myocardial rupture and hemopericardium associated with anticoagulant therapy; a post-mortem study.
B. Waldron
,
R. Fennell
,
B. Castleman
,
E. Bland
New England Journal of Medicine
1954
Corpus ID: 40895825
A DISTURBING feature of the occasional case of fatal hemopericardium following anticoagulant therapy for myocardial infarction is…
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1950
1950
Experiences with dicumarol in acute myocardial infarction.
E. Bresnick
,
L. Selverstone
,
B. Rapoport
,
K. Cheskey
,
H. Hultgren
,
H. Sise
New England Journal of Medicine
1950
Corpus ID: 44635014
NUMEROUS reports1 2 3 4 5 6 during the past few years have emphasized the value of Dicumarol therapy in reducing the mortality…
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1944
1944
UNCONTROLLABLE HEMORRHAGE AFTER DICOUMAROL THERAPY WITH AUTOPSY FINDINGS
E. L. Shlevin
,
M. Lederer
1944
Corpus ID: 58327276
Excerpt Interest in anti-coagulants as therapeutic agents has encouraged the trial of various substances in conditions…
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Highly Cited
1939
Highly Cited
1939
Determination of Prothrombin
A. Quick
1939
Corpus ID: 87475629
The author 1 developed a quantitative method for the determination of prothrombin based on the principle that the clotting time…
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