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Dicumarol

Known as: Bis(4-hydroxycoumarin-3-yl)methane, 2H-1-Benzopyran-2-one, 3,3'-methylenebis(4-hydroxy)-, bis-hydroxycoumarin 
An oral anticoagulant that interferes with the metabolism of vitamin K. It is also used in biochemical experiments as an inhibitor of reductases.
National Institutes of Health

Papers overview

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Review
2010
Review
2010
NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) is a widely-distributed FAD-dependent flavoprotein that promotes obligatory 2… Expand
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Highly Cited
2005
Highly Cited
2005
According to linear pharmacokinetics, the time course of plasma concentration of a drug, Cp,is expressed by a sum of exponential… Expand
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Review
1996
Review
1996
1. More than 300 coumarins have been identified from natural sources, especially green plants. The pharmacological and… Expand
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Highly Cited
1988
Highly Cited
1988
We describe a rapid and direct assay of NAD(P)H:(quinone-acceptor) oxidoreductase (EC 1.6.99.2) activity in cultured cells… Expand
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Highly Cited
1983
Highly Cited
1983
This investigation examined the effect of the anthracycline antitumor agents on reactive oxygen metabolism in rat heart. Oxygen… Expand
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Highly Cited
1980
Highly Cited
1980
2(3)-tert-Butyl-4-hydroxyanisole (BHA) is one of several widely used antioxidant food additives that protect against chemical… Expand
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Highly Cited
1976
Highly Cited
1976
  • J. Stenflo
  • The Journal of biological chemistry
  • 1976
  • Corpus ID: 7133375
Four proteins active in blood coagulation have long been known to require vitamin K for their proper biosynthesis: factors II… Expand
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Highly Cited
1974
Highly Cited
1974
A tetrapeptide, residues 6 to 9 in normal prothrombin, was isolated from the NH(2)-terminal, Ca(2+)-binding part of normal… Expand
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Highly Cited
1962
Highly Cited
1962
Abstract The isolation and properties of a flavoenzyme from rat liver is described. The enzyme, for which the name DT diaphorase… Expand
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Highly Cited
1959
Highly Cited
1959
THE STORY of Dieumarol* has been told several times by me in the past 17 years, and often by others. Like any good story it need… Expand
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