Dicumarol

Known as: Bis(4-hydroxycoumarin-3-yl)methane, 2H-1-Benzopyran-2-one, 3,3'-methylenebis(4-hydroxy)-, bis-hydroxycoumarin 
An oral anticoagulant that interferes with the metabolism of vitamin K. It is also used in biochemical experiments as an inhibitor of reductases.
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
The tumor suppressor p53 is a labile protein whose level is known to be regulated by the Mdm-2-ubiquitin-proteasome degradation… (More)
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Highly Cited
2002
Highly Cited
2002
Wild-type p53 is a tumor-suppressor gene that encodes a short-lived protein that, upon accumulation, induces growth arrest or… (More)
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Highly Cited
2002
Highly Cited
2002
The aim of this work was to study the effect of a sustained activation of AMP-activated protein kinase (AMPK) on liver cell… (More)
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Highly Cited
1997
Highly Cited
1997
Human spermatozoa possess a specialized capacity to generate reactive oxygen species (ROS) that is thought to be of significance… (More)
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Review
1996
Review
1996
1. More than 300 coumarins have been identified from natural sources, especially green plants. The pharmacological and… (More)
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Highly Cited
1978
Highly Cited
1978
According to linear pharmacokinetics, the time course of plasma concentration of a drug, Cp,is expressed by a sum of exponential… (More)
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Highly Cited
1976
Highly Cited
1976
Four proteins active in blood coagulation have long been known to require vitamin K for their proper biosynthesis: factors II… (More)
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Highly Cited
1974
Highly Cited
1974
A tetrapeptide, residues 6 to 9 in normal prothrombin, was isolated from the NH(2)-terminal, Ca(2+)-binding part of normal… (More)
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Highly Cited
1959
Highly Cited
1959
THE STORY of Dieumarol* has been told several times by me in the past 17 years, and often by others. Like any good story it need… (More)
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Highly Cited
1952
Highly Cited
1952
Different strains of staphylococci vary in ability to produce free coagulase. Methods are given for the selection of suitable… (More)
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