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Deoxyglucose

Known as: Deoxyglucose [Chemical/Ingredient], 2-deoxy-d-glucose, 2 Deoxyglucose 
A non-metabolizable glucose analog in which the hydroxyl group at position 2 of glucose is replaced by hydrogen, with potential glycolysis inhibiting… 
National Institutes of Health

Related topics

Related topics

36 relations

Narrower (21)

1,5-Anhydrosorbitol2,5-anhydroglucitol2-Fluoro-2-deoxy-D-glucose2-chloro-2-deoxyglucose

Broader (4)

AntimetabolitesAntiviral AgentsCarbohydratesGlucose
In BloodNCIt Antineoplastic Agent TerminologyProcess of secretionagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Targeting tumor metabolism with 2‐deoxyglucose in patients with castrate‐resistant prostate cancer and advanced malignancies
A profound difference between cancer and normal tissues is the preferential utilization of glycolysis by cancer cells. To… 
Highly Cited
2009
Highly Cited
2009
Comparison of 18F-fluoro-L-DOPA, 18F-fluoro-deoxyglucose, and 18F-fluorodopamine PET and 123I-MIBG scintigraphy in the localization of pheochromocytoma and paraganglioma.
CONTEXT Besides (123)I-metaiodobenzylguanidine (MIBG), positron emission tomography (PET) agents are available for the… 
Highly Cited
1998
Highly Cited
1998
Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes.
Circulating leptin secreted from adipocytes is correlated with fat mass and plasma insulin concentrations in humans and rodents… 
Highly Cited
1987
Highly Cited
1987
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.
Highly Cited
1981
Highly Cited
1981
Kainic acid induced limbic seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates
Review
1981
Review
1981
Localization of Functional Activity in the Central Nervous System by Measurement of Glucose Utilization with Radioactive Deoxyglucose
Sokoloff provided a review of his lab's deoxyglucose work so far: the theory and properties of the [14C] deoxyglucose and its… 
Highly Cited
1980
Highly Cited
1980
Activity‐dependent Energy Metabolism in Rat Posterior Pituitary Primarily Reflects Sodium Pump Activity
Sokoloff later noted, "This report provides evidence that the increase in glucose utilization evoked by functional activation in… 
Highly Cited
1973
Highly Cited
1973
Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells.
Highly Cited
1962
Highly Cited
1962
Regulation of Glucose Uptake by Muscle
Highly Cited
1957
Highly Cited
1957
Localization of the primary metabolic block produced by 2-deoxyglucose.
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