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Delta-Like Protein 4

Known as: Delta4, Drosophila Delta Homolog 4 
Delta-like protein 4 (685 aa, ~75 kDa) is encoded by the human DLL4 gene. This protein is involved in the initiation of notch signaling.
National Institutes of Health

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9 relations
Blood CirculationCell Differentiation processDLL4 geneHomo sapiens

Papers overview

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2004
2004
Membrane-bound Delta-4 Notch ligand reduces the proliferative activity of primitive human hematopoietic CD34+CD38low cells while maintaining their LTC-IC potential
To examine the role of the Notch ligand Delta-4 on hematopoietic stem cells, human CD34+CD38low cord blood cells were cocultured… 
2000
2000
Distinct Central Amphipathic α-Helices in Apolipoprotein A-I Contribute to the in Vivo Maturation of High Density Lipoprotein by Either Activating Lecithin-Cholesterol Acyltransferase or Binding…
Recombinant adenoviruses with cDNAs for human apolipoprotein A-I (wild type (wt) apoA-I) and three mutants, referred to as Δ4-5A… 
1978
1978
Dihydrotestosterone concentration in prostate cancer tissue as a predictor of tumor differentiation and hormonal dependency.
Tissue dihydrotestosterone and 5alpha-reductase (delta4-3-ketosteroid-5alpha-oxidoreductase) levels have been measured in… 
Highly Cited
1976
Highly Cited
1976
Puberty in girls: correlation of serum levels of gonadotropins, prolactin, androgens, estrogens, and progestins with physical changes.
Twenty-seven girls aged 8 to 18 were studied in a longitudinal prospective fashion. Serum samples were collected at 6 month… 
Highly Cited
1976
Highly Cited
1976
Minor and trace sterols in marine invertebrates 1. General methods of analysis
Highly Cited
1976
Highly Cited
1976
Steroid-protein interactions. XXXIV. Chemical modification of alpha1-acid glycoprotein for characterization of the progesterone binding site.
Highly Cited
1976
Highly Cited
1976
Male pseudohermaphroditism consistent with 17,20-desmolase deficiency.
A 16-year-old phenotypic female with XY genotype presented an unusual form of nonfamilial male pseudohermaphroditism. Seemingly a… 
1976
1976
Effects of estrogens on adrenal 3 beta-hydroxysteroid dehydrogenase in ovariectomized women.
The acute and chronic effects of estradiol (E2) on the serum levels of four delta5,3-beta hydroxysteroids and their four delta4… 
Highly Cited
1975
Highly Cited
1975
Persistent testicular delta5-isomerase-3beta-hydroxysteroid dehydrogenase (delta5-3beta-HSD) deficiency in the delta5-3beta-HSD form of congenital adrenal hyperplasia.
A partial testicular defect in testosterone secretion has been documented in a pubertal male with a congenital adrenal… 
1957
1957
Determination of delta4-3-keto-corticosteroids in human peripheral plasma by the isonicotinic acid hydrazide (INH) reaction.
THE purpose of this communication is to extend a previous report by the authors (1) on quantitative studies of various… 
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