DLL4 gene

Known as: Delta-Like 4 (Drosophila) Gene, DLL4, DELTA-LIKE 4 
This gene is involved in the notch signal transduction pathway.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Delta-like 4 (DLL4), a membrane-bound ligand belonging to the Notch signaling family, plays a fundamental role in vascular… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Arising from: J. Ridgway et al. 444, 1083–1087 (2006)10.1038/nature05313Delta-like 4 (DLL4)-mediated Notch signalling has emerged… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Previous studies have shown that blocking DLL4 signaling reduced tumor growth by disrupting productive angiogenesis. We developed… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
The development of arteries, veins and lymphatics from pre-existing vessels are intimately linked processes controlled by a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
The activation and differentiation of T cells are dependent upon numerous initiating events that are influenced by the immune… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
Highly Cited
2008
Highly Cited
2008
The Notch ligand, Dll4, is essential for angiogenesis during embryonic vascular development and is involved in tumour… (More)
  • figure 1
  • table 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2007
Review
2007
Anti-angiogenesis therapies have emerged as important treatment options for several types of tumours. To date, these therapies… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Vascular development is dependent on various growth factors and certain modifiers critical for providing arterial or venous… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Haploinsufficiency of Dll4, a vascular-specific Notch ligand, has shown that it is essential for embryonic vascular development… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
We report the cloning and characterization of a new member of the Delta family of Notch ligands, which we have named Dll4. Like… (More)
Is this relevant?