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DRD5 gene

Known as: DOPAMINE RECEPTOR D5, DOPAMINE RECEPTOR D1B, DRD1B 
This gene plays a regulatory role in adenylate cyclase activity and intracellular cAMP store accumulation. The gene is thought to act as a stimulus… Expand
National Institutes of Health

Related topics

Related topics

6 relations
G Protein-Coupled Receptor SignalingLigand BindingReceptor SignalingSignal Transduction
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Rare Copy Number Variation Discovery and Cross-Disorder Comparisons Identify Risk Genes for ADHD
A high-resolution analysis of copy number variation in patients with ADHD reveals new gene associations, few de novo mutations… Expand
Review
2009
Review
2009
The genetics of attention-deficit/hyperactivity disorder
Attention-deficit/hyperactivity disorder (ADHD) is a complex neurodevelopmental disorder that almost certainly represents the… Expand
Highly Cited
2006
Highly Cited
2006
Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD).
Molecular genetic investigations of attention deficit hyperactivity disorder (ADHD) have found associations with a variable… Expand
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Highly Cited
2004
Highly Cited
2004
Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes.
Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable, heterogeneous disorder of early onset, consisting of a… Expand
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Highly Cited
2004
Highly Cited
2004
Transmission disequilibrium testing of dopamine-related candidate gene polymorphisms in ADHD: confirmation of association of ADHD with DRD4 and DRD5
Attention-deficit hyperactivity disorder (ADHD) is one of the most common childhood behavioral disorders. Genetic factors… Expand
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Highly Cited
2003
Highly Cited
2003
Linkage disequilibrium mapping at DAT1, DRD5 and DBH narrows the search for ADHD susceptibility alleles at these loci
Abnormalities in dopaminergic neurotransmission are now accepted as factors in predisposing to ADHD. Evidence of associations… Expand
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Highly Cited
2002
Highly Cited
2002
Dopaminergic System Genes in ADHD: Toward a Biological Hypothesis
Converging evidence has implicated abnormalities of dopamine neurotransmission to the pathology of attention deficit… Expand
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Highly Cited
2000
Highly Cited
2000
Association and linkage of DRD4 and DRD5 with attention deficit hyperactivity disorder (ADHD) in a sample of Turkish children
The search for genetic factors predisposing to Attention Deficit Hyperactivity Disorder (ADHD) has focused on genes that regulate… Expand
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2000
2000
Antisociality, substance dependence, and the DRD5 gene: a preliminary study.
A pilot population-based study of a microsatellite polymorphism at the DRD5 locus in adult European-Americans showed its… Expand
Highly Cited
1999
Highly Cited
1999
Mapping susceptibility loci in attention deficit hyperactivity disorder: preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children
Attention deficit hyperactivity disorder (ADHD) is a common disorder of childhood characterized by inattention, excessive motor… Expand
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