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DRD2 wt Allele

Known as: Dopamine Receptor D2 wt Allele, D2R Gene, D(2) Dopamine Receptor Gene 
Human DRD2 wild-type allele is located within 11q23 and is approximately 66 kb in length. This allele, which encodes D(2) dopamine receptor protein… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (1)

DRD2 gene
G Protein-Coupled Receptor SignalingHomo sapiensLigand BindingReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Treadmill exercise elevates striatal dopamine D2 receptor binding potential in patients with early Parkinson’s disease
We have previously demonstrated changes in dopaminergic neurotransmission after intensive exercise in the 1-methyl-4-phenyl-1,2,3… 
Highly Cited
2011
Highly Cited
2011
Decreased dopamine activity predicts relapse in methamphetamine abusers
Studies in methamphetamine (METH) abusers showed that the decreases in brain dopamine (DA) function might recover with protracted… 
Highly Cited
2005
Highly Cited
2005
D2 Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways
Regulator of G-protein signaling 9-2 (RGS9-2), a member of the RGS family of Gα GTPase accelerating proteins, is expressed… 
Highly Cited
2002
Highly Cited
2002
Changes in Extracellular Dopamine Induced by Morphine and Cocaine: Crucial Control by D2 Receptors
An increase of extracellular dopamine (DA) concentration is a major neurobiological substrate of the addictive properties of… 
Review
2000
Review
2000
Imaging transgene expression with radionuclide imaging technologies.
A variety of imaging technologies are being investigated as tools for studying gene expression in living subjects. Noninvasive… 
Highly Cited
1999
Highly Cited
1999
Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals
Reporter genes (eg β-galactosidase, chloramphenicol-acetyltransferase, green fluorescent protein, luciferase) play critical roles… 
Review
1999
Review
1999
Assays for noninvasive imaging of reporter gene expression.
Highly Cited
1998
Highly Cited
1998
Locomotor Activity in D2 Dopamine Receptor-Deficient Mice Is Determined by Gene Dosage, Genetic Background, and Developmental Adaptations
Locomotor activity is a polygenic trait that varies widely among inbred strains of mice (Flint et al., 1995). To characterize the… 
Highly Cited
1997
Highly Cited
1997
Abnormal Synaptic Plasticity in the Striatum of Mice Lacking Dopamine D2 Receptors
Dopamine D2 receptors (D2Rs) are of crucial importance in the striatal processing of motor information received from the cortex… 
Highly Cited
1991
Highly Cited
1991
Association of the A1 allele of the D2 dopamine receptor gene with severe alcoholism.
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