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DRD2 wt Allele

Known as: Dopamine Receptor D2 wt Allele, D2R Gene, D(2) Dopamine Receptor Gene 
Human DRD2 wild-type allele is located within 11q23 and is approximately 66 kb in length. This allele, which encodes D(2) dopamine receptor protein… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (1)

DRD2 gene
G Protein-Coupled Receptor SignalingHomo sapiensLigand BindingReceptor Signaling

Papers overview

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Highly Cited
2017
Highly Cited
2017
Cell imaging of dopamine receptor using agonist labeling iridium(iii) complex
A long-lived complex 13 could selectively bind to dopamine receptors (D1R/D2R) and monitor their internalization in living cells. 
Highly Cited
2015
Highly Cited
2015
Opposing relationships of BMI with BOLD and dopamine D2/3 receptor binding potential in the dorsal striatum
Findings from clinical and preclinical studies converge to suggest that increased adiposity and/or exposure to a high fat diet… 
Highly Cited
2011
Highly Cited
2011
N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity…
N-(3-fluoro-4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazine-1-yl)butyl)arylcarboxamides were prepared and evaluated for binding… 
Highly Cited
2011
Highly Cited
2011
Neurotensin Triggers Dopamine D2 Receptor Desensitization through a Protein Kinase C and β-Arrestin1-dependent Mechanism*
The peptide neurotensin (NT) is known to exert a potent excitatory effect on the dopaminergic system by inhibiting D2 dopamine… 
Highly Cited
2007
Highly Cited
2007
Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization
Highly Cited
2001
Highly Cited
2001
Adenosine A2A agonist CGS 21680 decreases the affinity of dopamine D2 receptors for dopamine in human striatum
Adenosine A2A receptors (A2AR) and dopamine D2 receptors (D2R) are highly concentrated in the striatum, where they are co… 
Highly Cited
2001
Highly Cited
2001
Quantitative imaging of gene induction in living animals
Methods to repeatedly, non-invasively, and quantitatively image gene expression in living animals are rapidly emerging and should… 
Review
1999
Review
1999
Radiotracer imaging of dopaminergic transmission in neuropsychiatric disorders
Abstract This article will review the capabilities and accomplishments of radiotracer imaging with single photon emission… 
1994
1994
Differential influence of haloperidol and sulpiride on dopamine receptors and peptide mRNA levels in the rat striatum and pituitary.
Highly Cited
1991
Highly Cited
1991
D2 dopamine receptor gene expression in the rat striatum during ontogeny: an in situ hybridization study.
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