DRD2 wt Allele

Known as: Dopamine Receptor D2 wt Allele, D2R Gene, D(2) Dopamine Receptor Gene 
Human DRD2 wild-type allele is located within 11q23 and is approximately 66 kb in length. This allele, which encodes D(2) dopamine receptor protein… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
05010019892017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
The specific functions of dopamine D2 receptor–positive (D2R) striatopallidal neurons remain poorly understood. Using a genetic… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Since the unexpected discovery of the antipsychotic activity of chlorpromazine, a variety of therapeutic agents have been… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Increased activity of D2 receptors (D2Rs) in the striatum has been linked to the pathophysiology of schizophrenia. To determine… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Dopamine-glutamate interactions in the neostriatum determine psychostimulant action, but the underlying molecular mechanisms… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
There is evidence for strong functional antagonistic interactions between adenosine A2A receptors (A2ARs) and dopamine D2… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Somatostatin and dopamine are two major neurotransmitter systems that share a number of structural and functional characteristics… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Reporter genes (eg β-galactosidase, chloramphenicol-acetyltransferase, green fluorescent protein, luciferase) play critical roles… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Locomotor activity is a polygenic trait that varies widely among inbred strains of mice (). To characterize the role of D2… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 4
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Schizophrenia is believed to involve altered activation of dopamine receptors, and support for this hypothesis conies from the… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Dopamine D2 receptors (D2Rs) are of crucial importance in the striatal processing of motor information received from the cortex… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?