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DOCK1 protein
Known as:
DOCK180
, Downstream of CRK-Binding Protein, 180-kD
, 180 kDa Protein Downstream of CRK
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Dedicator of cytokinesis protein 1 (1865 aa, ~215 kDa) is encoded by the human DOCK1 gene. This protein is involved in phagocytosis, apoptosis and…
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National Institutes of Health
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Related topics
Related topics
7 relations
Apoptosis
Cell Surface Extensions
DOCK1 gene
Focal adhesion pathway
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
ARF1 and ARF6 regulate recycling of GRASP/Tamalin and the Rac1-GEF Dock180 during HGF-induced Rac1 activation
Emily J Koubek
,
L. Santy
Small GTPases
2018
Corpus ID: 26962090
ABSTRACT Hepatocyte growth factor (HGF) is a potent signaling factor that acts on epithelial cells, causing them to dissociate…
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2015
2015
Regulatory role of guanine nucleotide exchange factor (GEF) Dock180 phosphorylation on Tyr/Ser in mediation of gastric mucosal Rac1 activation in response to Helicobacter pylori and ghrelin
B. Slomiany
,
A. Slomiany
InflammoPharmacology
2015
Corpus ID: 1853706
A small GTPase, Rac1, is recognized as an important modulator of the inflammatory responses to bacterial lipopolysaccharide (LPS…
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2012
2012
ELMO Recruits Actin Cross-linking Family 7 (ACF7) at the Cell Membrane for Microtubule Capture and Stabilization of Cellular Protrusions*
Y. Margaron
,
Nadine Fradet
,
J. Côté
Journal of Biological Chemistry
2012
Corpus ID: 41706515
Background: ELMO and DOCK180 synergize to promote Rac-dependent cell migration. Results: ELMO synergize with a novel interacting…
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2012
2012
The C-terminal polyproline-containing region of ELMO contributes to an increase in the life-time of the ELMO-DOCK complex.
M. Sévajol
,
J. Reiser
,
+5 authors
D. Housset
Biochimie
2012
Corpus ID: 205997428
Highly Cited
2010
Highly Cited
2010
DOCK180 Is a Rac Activator That Regulates Cardiovascular Development by Acting Downstream of CXCR4
F. Sanematsu
,
M. Hirashima
,
+13 authors
Y. Fukui
Circulation Research
2010
Corpus ID: 27736045
Rationale: During embryogenesis, the CXC chemokine ligand (CXCL)12 acts on endothelial cells to control cardiac development and…
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2010
2010
Rac1 Is Essential for Basement Membrane-Dependent Epiblast Survival
Xiaowen He
,
Jie Liu
,
+9 authors
Shaohua Li
Molecular and Cellular Biology
2010
Corpus ID: 35261442
ABSTRACT During murine peri-implantation development, the egg cylinder forms from a solid cell mass by the apoptotic removal of…
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2009
2009
Regulation of focal adhesion and cell migration by ANKRD28-DOCK180 interaction
E. Kiyokawa
,
M. Matsuda
Cell Adhesion & Migration
2009
Corpus ID: 46428713
DOCK180 is an atypical guanine nucleotide exchange factor of Rac1 identified originally as one of the two major proteins bound to…
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2005
2005
Rac and cell migration: CDM proteins integrate signals
H. Bourne
Nature Cell Biology
2005
Corpus ID: 23789032
Cell migration requires that Rac GTPases promote formation of actin polymers at the cell's leading edge. An activator of Rac…
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2002
2002
GEF without a Dbl domain?
V. Braga
Nature Cell Biology
2002
Corpus ID: 332190
Guanine nucleotide-exchange factors (GEFs) interact with and activate members of the Rho family of small GTPases through Dbl…
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1976
1976
The selection of shelter place by the house cricket.
M. Kieruzel
Acta Neurobiologiae Experimentalis
1976
Corpus ID: 26582366
The stimuli acting upon the choice of shelter and resting place by the house cricket, Acheta domesticus (L.) were analysed. The…
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