DOCK1 gene

Known as: DOWNSTREAM OF CRK, 180-KD, Dedicator of Cytokinesis 1 Gene, DEDICATOR OF CYTOKINESIS 1 
This gene is involved in apoptosis, cell motility/migration and phagocytosis.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Dock1 (also known as Dock180) is a prototypical member of a new family of atypical Rho GTPase activators. Genetic studies in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2008
2008
The mammalian DOCK180 protein belongs to an evolutionarily conserved protein family, which together with ELMO proteins, is… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Myoblast fusion follows a defined sequence of events that is strikingly similar in vertebrates and invertebrates. Genetic… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Shigella use a special mechanism to invade epithelial cells called 'the trigger mechanism of entry', which allows epithelial… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Cell motility requires extensions of the plasma membrane driven by reorganization of the actin cytoskeleton. Small GTPases… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Cell migration is essential throughout embryonic and adult life. In numerous cell systems, the small GTPase Rac is required for… (More)
Is this relevant?
Review
2004
Review
2004
Rho GTPases act as key regulators of cellular biochemistry by determining the timing, direction, and amplitude of signal… (More)
Is this relevant?
2004
2004
In a yeast two-hybrid system screen for Cdc42-interacting proteins, we identified a protein with similarity to the CrkII-binding… (More)
Is this relevant?
1996
1996
CRK is a human homolog of chichen v-Crk, which is an adaptor protein. The SH2 domain of CRK binds to several tyrosine… (More)
Is this relevant?
Review
1996
Review
1996
v-Crk, identified as an oncogene product of the CT10 retrovirus, became the first example of an adaptor protein. It consists… (More)
Is this relevant?