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DOCK1 gene

Known as: DOWNSTREAM OF CRK, 180-KD, Dedicator of Cytokinesis 1 Gene, DEDICATOR OF CYTOKINESIS 1 
This gene is involved in apoptosis, cell motility/migration and phagocytosis.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Dock1 (also known as Dock180) is a prototypical member of a new family of atypical Rho GTPase activators. Genetic studies in… Expand
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Highly Cited
2007
Highly Cited
2007
A distinct feature of malignant gliomas is the intrinsic ability of single tumor cells to disperse throughout the brain… Expand
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Highly Cited
2005
Highly Cited
2005
Cell motility requires extensions of the plasma membrane driven by reorganization of the actin cytoskeleton. Small GTPases… Expand
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Highly Cited
2005
Highly Cited
2005
CDM (CED-5, Dock180, Myoblast city) family members have been recently identified as novel, evolutionarily conserved guanine… Expand
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Highly Cited
2004
Highly Cited
2004
Cell migration is essential throughout embryonic and adult life. In numerous cell systems, the small GTPase Rac is required for… Expand
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Highly Cited
2002
Highly Cited
2002
Mammalian Dock180 and ELMO proteins, and their homologues in Caenorhabditis elegans and Drosophila melanogaster, function as… Expand
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Highly Cited
2002
Highly Cited
2002
Mammalian DOCK180 protein and its orthologues Myoblast City (MBC) and CED-5 in Drosophila and Caenorhabditis elegans… Expand
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Highly Cited
2001
Highly Cited
2001
The α5 chain-containing laminin isoforms, laminins-10 and -11 (laminin-10/11), are the major components of the basement membrane… Expand
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Highly Cited
1998
Highly Cited
1998
During programmed cell death, cell corpses are rapidly engulfed. This engulfment process involves the recognition and subsequent… Expand
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Highly Cited
1996
Highly Cited
1996
CRK belongs to a family of adaptor proteins that consist mostly of SH2 and SH3 domains. Far Western blotting with CRK SH3 has… Expand
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