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DOCK1 gene

Known as: DOWNSTREAM OF CRK, 180-KD, Dedicator of Cytokinesis 1 Gene, DEDICATOR OF CYTOKINESIS 1 
This gene is involved in apoptosis, cell motility/migration and phagocytosis.
National Institutes of Health

Related topics

Related topics

4 relations
ApoptosisCell Surface ExtensionsDOCK1 proteinDOCK6 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
ARF1 and ARF6 regulate recycling of GRASP/Tamalin and the Rac1-GEF Dock180 during HGF-induced Rac1 activation
ABSTRACT Hepatocyte growth factor (HGF) is a potent signaling factor that acts on epithelial cells, causing them to dissociate… 
2018
2018
Activation of Rac 1 by Src-dependent phosphorylation of Dock 180 Y 1811 mediates PDGFR a-stimulated glioma tumorigenesis in mice and humans
Two hallmarks of glioblastoma multiforme, the most common malignant brain cancer in humans, are aggressive growth and the ability… 
2018
2018
Silencing of dedicator of cytokinesis (DOCK180) obliterates pregnancy by interfering with decidualization due to blockage of nuclear entry of autoimmune regulator (AIRE)
Dedicator of cytokinesis (DOCK 180) involved in cytoskeletal reorganization is primarily a cytosolic molecule. It is recently… 
2017
2017
RHOG-DOCK1-RAC1 Signaling Axis Is Perturbed in DHEA-Induced Polycystic Ovary in Rat Model
The function of RHOG, a RAC1 activator, was explored in the ovary during ovarian follicular development and pathological… 
2013
2013
The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo
Podocytes are specialized kidney cells that form the kidney filtration barrier through the connection of their foot processes… 
2012
2012
The C-terminal polyproline-containing region of ELMO contributes to an increase in the life-time of the ELMO-DOCK complex.
Highly Cited
2010
Highly Cited
2010
DOCK180 Is a Rac Activator That Regulates Cardiovascular Development by Acting Downstream of CXCR4
Rationale: During embryogenesis, the CXC chemokine ligand (CXCL)12 acts on endothelial cells to control cardiac development and… 
2008
2008
Identification of DOCK4 and its splicing variant as PIP3 binding proteins
DOCK4, a member of DOCK180 family proteins, was originally identified as a product of a gene deleted during tumor progression… 
Review
2006
Review
2006
Year : 2004 Dock 180 and ELMO 1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration
Cell migration is essential throughout embryonic and adult life. In numerous cell systems, the small GTPase Rac is required for… 
1996
1996
Chromosomal mapping of the gene encoding DOCK180, a major Crk-binding protein, to 10q26.13-q26.3 by fluorescence in situ hybridization.
This report describes the localization of the gene encoding DOCK180, a major Crk-binding protein, to human chromosome 10q26.13… 
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