Skip to search formSkip to main contentSkip to account menu

DNMT3A gene

Known as: DNMT3A, DNA METHYLTRANSFERASE 3A, DNA (cytosine-5-)-methyltransferase 3 alpha 
This gene is involved in epigenetic modification of DNA.
National Institutes of Health

Related topics

Related topics

5 relations
DNA (Cytosine-5)-Methyltransferase 3ADNA MethylationDNA methyltransferase 3AMethylation

Narrower (1)

DNMT3A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
The clinical impact of mutant DNMT3A R882 variant allele frequency in acute myeloid leukaemia
Barbui, T., Carobbio, A., Finazzi, G., Vannucchi, A.M., Barosi, G., Antonioli, E., Guglielmelli, P., Pancrazzi, A., Salmoiraghi… 
2017
2017
20(S)-Rg3 blocked epithelial-mesenchymal transition through DNMT3A/miR-145/FSCN1 in ovarian cancer
Epithelial-mesenchymal transition (EMT) is one of the key mechanisms mediating cancer progression. MicroRNAs (miRs) are essential… 
2017
2017
Clinical implications of DNMT3A mutations in a Southeast Asian cohort of acute myeloid leukaemia patients
Aims In recent years, genomic technologies have enabled the identification of mutations in acute myeloid leukaemia (AML). DNMT3A… 
2017
2017
Myelomonocytic leukemia with intracytoplasmic crystalline inclusions, double minute chromosomes and MYC amplification
2014
2014
Mutation Analysis of JAK2V617F, FLT3-ITD, NPM1, and DNMT3A in Chinese Patients with Myeloproliferative Neoplasms
Since the discovery of JAK2V617F tyrosine kinase-activating mutation, several genes have been found mutated in myeloproliferative… 
2013
2013
Effects of Somatic Mutations Are Associated with SNP in the Progression of Individual Acute Myeloid Leukemia Patient: The Two-Hit Theory Explains Inherited Predisposition to Pathogenesis
This study evaluated the effects of somatic mutations and single nucleotide polymorphisms (SNPs) on disease progression and tried… 
2013
2013
Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT 3 A mutations
  • 2013
  • Corpus ID: 8942982
Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations Martin Neumann, Sandra Heesch, Cornelia Schlee… 
2012
2012
DNMT3A rs36012910 A>G polymorphism and gastric cancer susceptibility in a Chinese population
DNA-methyltransferase (DNMT)-3A plays a crucial role in embryonic development and aberrant DNA methylation in carcinogenesis… 
2012
2012
Prognostic Impact of Mutations in a Large Series of Patients with Myelofibrosis
Abstract 431 Background. Primary myelofibrosis (PMF) has the worst prognosis among myeloproliferative neoplasms with median… 
2011
2011
[Analysis of DNMT3a gene mutations in acute myelogenous leukemia].
This study was purposed to investigate the mutational status of DNA methyltransferase (DNMT3a) gene and the clinical features of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)