DNMT3A gene

Known as: DNMT3A, DNA METHYLTRANSFERASE 3A, DNA (cytosine-5-)-methyltransferase 3 alpha 
This gene is involved in epigenetic modification of DNA.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Several genetic alterations characteristic of leukemia and lymphoma have been detected in the blood of individuals without… (More)
  • table 1
  • figure 1
  • table 8
  • figure 3
  • table 13
Is this relevant?
2014
2014
Mutations in DNMT3A, the gene encoding DNA methyltransferase 3 alpha, have been identified as molecular drivers in acute myeloid… (More)
  • table I
  • table II
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Early T-cell precursor (ETP) acute lymphoblastic leukemia (ALL) is a high-risk subgroup of T-lineage ALL characterized by… (More)
  • figure 1
  • table 1
Is this relevant?
Highly Cited
2013
Highly Cited
2013
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive and heterogeneous disease. The diagnosis is predominantly based on… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2012
Highly Cited
2012
The prevalence, the prognostic effect, and interaction with other molecular markers of DNMT3A mutations was studied in 415… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
Highly Cited
2012
Highly Cited
2012
PURPOSE To determine the frequency of DNMT3A mutations, their associations with clinical and molecular characteristics and… (More)
  • table 1
  • table 1
  • table 2
  • figure 1
  • table 3
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Loss of the de novo DNA methyltransferases Dnmt3a and Dnmt3b in embryonic stem cells obstructs differentiation; however, the role… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Since the discovery of the gain-of-function mutation JAK2 V617F in 2005, an increasing number of mutations have been described in… (More)
  • table 1
  • table 2
  • figure 1
  • table 1
Is this relevant?
Highly Cited
2011
Highly Cited
2011
BACKGROUND Mutations in the DNMT3A, TET2, IDH1, and IDH2 genes carry prognostic significance and occur frequently in adult acute… (More)
  • table I
  • figure 1
  • table II
  • figure 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Imprinted genes are epigenetically marked during gametogenesis so that they are exclusively expressed from either the paternal or… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?