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DNA methyltransferase 3A

Known as: DNA (cytosine-5)-methyltransferase 3A, human 
National Institutes of Health

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DNMT3A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Role of MicroRNA-143 in Nerve Injury-Induced Upregulation of Dnmt3a Expression in Primary Sensory Neurons
Peripheral nerve injury increased the expression of the DNA methyltransferase 3A (Dnmt3a) mRNA and its encoding Dnmt3a protein in… 
2017
2017
5-Aza-2’-deoxycytidine in the medial prefrontal cortex regulates alcohol-related behavior and Ntf3-TrkC expression in rats
Recent studies have indicated that DNA methylation plays an important role in the development of alcohol abuse. 5-Aza-2… 
2015
2015
Hypoxia mimetic deferoxamine influences the expression of histone acetylation- and DNA methylation-associated genes in osteoblasts
Abstract Purpose of the study: Sufficient oxygen supply to bone tissue is essential for normal bone development and efficient… 
2014
2014
DNMT3a epigenetic program regulates the HIF-2α oxygen-sensing pathway and the cellular response to hypoxia
Significance DNA methyltransferase 3a (DNMT3a) mediates the de novo methylation of DNA to regulate gene expression and maintain… 
2014
2014
Folate deficiency exacerbates apoptosis by inducing hypomethylation and resultant overexpression of DR4 together with altering DNMTs in Alzheimer's disease.
This study was to evaluate patterns of gene expression and promoter methylation of DR4 from peripheral circulating blood… 
2012
2012
HDAC1/DNMT3A-containing complex is associated with suppression of Oct4 in cervical cancer cells
Octamer-binding transcription factor 4 (Oct4), an important embryonic transcriptional factor, is highly expressed in several… 
2011
2011
microRNA-450a targets DNA methyltransferase 3a in hepatocellular carcinoma.
microRNAs (miRNAs) have been proven to play key regulatory roles in hepatocarcinogenesis. In the present study, the possible role… 
2010
2010
Identification of a second DNA binding site in human DNA methyltransferase 3A by substrate inhibition and domain deletion.
2010
2010
Developing multidrug-resistant cells and exploring correlation between BCRP/ABCG2 over-expression and DNA methyltransferase.
Expression of breast cancer resistance protein/ATP-binding cassette sub-family G member 2 (BCRP/ABCG2) is the major cause of… 
Highly Cited
2004
Highly Cited
2004
Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription.
The de novo DNA methyltransferase Dnmt3a is one of three mammalian DNA methyltransferases that has been shown to play crucial… 
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