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DNA methyltransferase 3A

Known as: DNA (cytosine-5)-methyltransferase 3A, human 
National Institutes of Health

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DNMT3A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Methionine Supply During Late-Gestation Triggers Offspring Sex-Specific Divergent Changes in Metabolic and Epigenetic Signatures in Bovine Placenta.
Background Nonruminant male and female offspring respond differently to gestational nutrition, with placenta contributing to the… 
2016
2016
MicroRNA-101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A
It is well established that transcriptional silencing of critical tumor suppressor genes by DNA methylation is a fundamental… 
Highly Cited
2014
Highly Cited
2014
MicroRNA-143 is downregulated in breast cancer and regulates DNA methyltransferases 3A in breast cancer cells
MicroRNAs (miRNAs) are small non-protein-coding RNAs that regulate expression of a wide variety of genes including those involved… 
Highly Cited
2013
Highly Cited
2013
miR-101 is down-regulated by the hepatitis B virus x protein and induces aberrant DNA methylation by targeting DNA methyltransferase 3A.
Highly Cited
2013
Highly Cited
2013
MicroRNA miR-29c Down-Regulation Leading to De-Repression of Its Target DNA Methyltransferase 3a Promotes Ischemic Brain Damage
Recent studies showed that stroke extensively alters cerebral microRNA (miRNA) expression profiles and several miRNAs play a role… 
2012
2012
RNA modulation of the human DNA methyltransferase 3A
DNA methyltransferase 3A (DNMT3A) is one of two human de novo DNA methyltransferases essential for transcription regulation… 
2011
2011
microRNA-450a targets DNA methyltransferase 3a in hepatocellular carcinoma.
microRNAs (miRNAs) have been proven to play key regulatory roles in hepatocarcinogenesis. In the present study, the possible role… 
Highly Cited
2009
Highly Cited
2009
Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells
Small RNAs targeted to gene promoters in human cells can mediate transcriptional gene silencing (TGS) by directing silent state… 
Highly Cited
2008
Highly Cited
2008
Loss of pericentromeric DNA methylation pattern in human glioblastoma is associated with altered DNA methyltransferases expression and involves the stem cell compartment
Cancer is generally characterized by loss of CG dinucleotides methylation resulting in a global hypomethylation and the… 
Highly Cited
2004
Highly Cited
2004
Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription.
The de novo DNA methyltransferase Dnmt3a is one of three mammalian DNA methyltransferases that has been shown to play crucial… 
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