DNA methyltransferase 3A

Known as: DNA (cytosine-5)-methyltransferase 3A, human 
 
National Institutes of Health

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DNMT3A gene

Papers overview

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2019
2019
Methionine Supply During Late-Gestation Triggers Offspring Sex-Specific Divergent Changes in Metabolic and Epigenetic Signatures in Bovine Placenta.
Background Nonruminant male and female offspring respond differently to gestational nutrition, with placenta contributing to the… (More)
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Highly Cited
2013
Highly Cited
2013
miR-101 is down-regulated by the hepatitis B virus x protein and induces aberrant DNA methylation by targeting DNA methyltransferase 3A.
The hepatitis B virus x (HBx) protein has been implicated in HBV-related hepatocellular carcinoma (HCC) pathogenesis. However… (More)
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2013
2013
MicroRNA miR-29c Down-Regulation Leading to De-Repression of Its Target DNA Methyltransferase 3a Promotes Ischemic Brain Damage
Recent studies showed that stroke extensively alters cerebral microRNA (miRNA) expression profiles and several miRNAs play a role… (More)
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2013
2013
Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A.
Although tumour suppressor gene hypermethylation is a universal feature of cancer cells, little is known about the necessary… (More)
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2012
2012
RNA modulation of the human DNA methyltransferase 3A
DNA methyltransferase 3A (DNMT3A) is one of two human de novo DNA methyltransferases essential for transcription regulation… (More)
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2011
2011
microRNA-450a targets DNA methyltransferase 3a in hepatocellular carcinoma.
microRNAs (miRNAs) have been proven to play key regulatory roles in hepatocarcinogenesis. In the present study, the possible role… (More)
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2011
2011
Caloric restriction attenuates age-related changes of DNA methyltransferase 3a in mouse hippocampus
Recent studies have suggested that DNA methylation is implicated in age-related changes in gene expression as well as in… (More)
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2010
2010
Identification of a second DNA binding site in human DNA methyltransferase 3A by substrate inhibition and domain deletion.
The human DNA methyltransferase 3A (DNMT3A) is essential for establishing DNA methylation patterns. Knowing the key factors… (More)
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2009
Highly Cited
2009
Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells
Small RNAs targeted to gene promoters in human cells can mediate transcriptional gene silencing (TGS) by directing silent state… (More)
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Highly Cited
2004
Highly Cited
2004
Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription.
The de novo DNA methyltransferase Dnmt3a is one of three mammalian DNA methyltransferases that has been shown to play crucial… (More)
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