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DNA Alkylation

DNA Alkylation involves the addition of alkyl groups to any of several vulnerable positions on all four of the DNA bases. Alkylating agents can also… 
National Institutes of Health

Papers overview

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2015
2015
In this present paper, the results oligomerizaton and alkylation of decene-1 in the presence of recyclable chloroaluminate type… 
1987
1987
: A possible role of chromosomal abnormalities in activation of cellular oncogenes is discussed. Data about the types of… 
1986
1986
Recently, it has been reported that changes in DNA higher-order structure and DNA-associated protein structure in methylmethane… 
1986
1986
Recent laboratory studies have shown that the major in-vivo DNA alkylation product of vinyl chloride is the 7-(2-oxoethyl… 
1986
1986
The metabolism and reaction with DNA of N-nitrosodimethylamine (NDMA) and N-nitrosomethylbenzylamine (NMBzA) were investigated in… 
1983
1983
: Alkylating agents have proved useful as models, especially for low molecular weight mutagens and carcinogens, to probe… 
1983
1983
The effect of CCl4 pretreatment (dose range from 0.5 to 2.0 ml/kg body weight) on the pathways of dimethylnitrosamine (DMN… 
1983
1983
Alkylating agents have proved useful as models, especially for low molecular weight mutagens and carcinogens, to probe molecular… 
1982
1982
The removal of DNA adducts is an essential step of DNA repair following exposure to chloroethylnitrosoureas. Adduct removal was… 
1979
1979
Abstract The effect of nitrosourea carbamoylating activity on the repair of nitrosourea-induced DNA alkylation damage has been…