DNA Adducts

Known as: Drug-DNA Adduct, Carcinogen-DNA Adducts, DNA Adduct 
The products of chemical reactions that result in the addition of extraneous chemical groups to DNA.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2018
05019762018

Papers overview

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Review
2014
Review
2014
Exocyclic etheno-DNA adducts are mutagenic and carcinogenic and are formed by the reaction of lipidperoxidation (LPO) products… (More)
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Highly Cited
2007
Highly Cited
2007
32P-postlabeling analysis is an ultrasensitive method for the detection and quantitation of carcinogen–DNA adducts. It consists… (More)
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Highly Cited
2006
Highly Cited
2006
Doxorubicin (Adriamycin) is one of the most commonly used chemotherapeutic drugs and exhibits a wide spectrum of activity against… (More)
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Highly Cited
2001
Highly Cited
2001
Individuals differ widely in their ability to repair DNA damage, and DNA-repair deficiency may be involved in modulating cancer… (More)
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Highly Cited
1996
Highly Cited
1996
A number of promutagenic exocyclic DNA adducts have recently been detected in both humans and rodents without carcinogen… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND The antitumor drug cis-diamminedichloroplatinum(II) (cis-DDP or cisplatin) exerts its cytotoxic effects through the… (More)
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Highly Cited
1992
Highly Cited
1992
An improved high-performance liquid chromatography/fluorometric assay has been established to quantitate the benzo(a)pyrene (BP… (More)
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Highly Cited
1991
Highly Cited
1991
The prevalence of covalent modifications to DNA (carcinogen-DNA adducts) in 42 human urinary bladder biopsy samples was… (More)
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1985
1985
Coke oven workers are exposed to high levels of carcinogenic polycyclic aromatic hydrocarbons, including benzo[a]pyrene (B[a]P… (More)
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Highly Cited
1982
Highly Cited
1982
A newly developed enzymatic 32P-postlabeling method was applied to the analysis of DNA's containing non-radioactive arylamine… (More)
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