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DNA (Cytosine-5)-Methyltransferase 3A

Known as: DNA Methyltransferase HsaIIIA, M.HsaIIIA, DNMT3A 
DNA (cytosine-5)-methyltransferase 3A protein (909 aa, ~102 kDa) is encoded by the human DNMT3A gene. This soluble, nuclear protein is involved in… 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Alcohol exposure affects neuronal plasticity in the adult and developing brain. Astrocytes play a major role in modulating… 
2013
2013
DNMT3 proteins are de novo DNA methyltransferases that are responsible for the establishment of DNA methylation patterns in… 
Highly Cited
2012
Highly Cited
2012
Purpose: Overexpression of DNA 5′-cytosine-methyltransferase 3A (DNMT3A), which silences genes including tumor suppressor genes… 
Highly Cited
2006
Highly Cited
2006
DNA methylation is a major epigenetic mechanism that has been suggested to control developmental gene regulation during… 
Highly Cited
2006
Highly Cited
2006
Dnmt3a and Dnmt3b are two major de novo DNA methyltransferases essential for embryonic development in mammals. It has been shown… 
Highly Cited
2002
Highly Cited
2002
The expression of metallothionein-I (MT-I), a known antioxidant, was suppressed in a transplanted rat hepatoma because of… 
Highly Cited
2001
Highly Cited
2001
ABSTRACT We have utilized the Escherichia coli lacrepressor-operator system to test whether protein binding can interfere with de… 
Review
2001
Review
2001
Epigenetic control of gene expression in animals and plants is often correlated with changes in cytosine methylation at specific…