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MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.
- F. Meng, R. Henson, H. Wehbe-Janek, K. Ghoshal, S. Jacob, T. Patel
- BiologyGastroenterology
- 1 August 2007
TLDR
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver.
- S. Hsu, Bo Wang, K. Ghoshal
- Biology, MedicineThe Journal of clinical investigation
- 1 August 2012
TLDR
MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1*♦
- Tyler E. Miller, K. Ghoshal, S. Majumder
- BiologyJournal of Biological Chemistry
- 31 October 2008
TLDR
Downregulation of miR‐122 in the rodent and human hepatocellular carcinomas
- Huban Kutay, Shoumei Bai, K. Ghoshal
- Biology, MedicineJournal of cellular biochemistry
- 15 October 2006
TLDR
5-Aza-Deoxycytidine Induces Selective Degradation of DNA Methyltransferase 1 by a Proteasomal Pathway That Requires the KEN Box, Bromo-Adjacent Homology Domain, and Nuclear Localization Signal
- K. Ghoshal, J. Datta, S. Jacob
- Biology, ChemistryMolecular and Cellular Biology
- 1 June 2005
TLDR
A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation.
- J. Datta, K. Ghoshal, S. Jacob
- Biology, ChemistryCancer research
- 15 May 2009
TLDR
Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis.
- J. Datta, Huban Kutay, S. Jacob
- Biology, ChemistryCancer research
- 1 July 2008
TLDR
TGFβ mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3
- Bo Wang, S. Hsu, K. Ghoshal
- Biology, MedicineOncogene
- 12 November 2009
TLDR
Role of microRNA‐155 at early stages of hepatocarcinogenesis induced by choline‐deficient and amino acid–defined diet in C57BL/6 mice
- Bo Wang, S. Majumder, S. Jacob
- Biology, MedicineHepatology
- 1 October 2009
MicroRNAs (miRs) are conserved, small (20‐25 nucleotide) noncoding RNAs that negatively regulate expression of messenger RNAs (mRNAs) at the posttranscriptional level. Aberrant expression of certain…
Low levels of miR‐92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma
- Sharmistha Pal, R. Baiocchi, J. Byrd, M. Grever, S. Jacob, S. Sif
- BiologyThe EMBO journal
- 8 August 2007
TLDR
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