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DKC1 gene

Known as: H/ACA ribonucleoprotein complex subunit 4, NOPP140-ASSOCIATED PROTEIN, 57-KD, XAP101 
This gene is involved in both H/ACA small nucleolar RNA ribonucleoprotein assembly and telomerase stabilization and maintenance.
National Institutes of Health

Related topics

Related topics

6 relations
DKC1 protein, humanH/ACA Ribonucleoprotein Complex Subunit 4, humanLigand BindingRNA Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Human intron-encoded Alu RNAs are processed and packaged into Wdr79-associated nucleoplasmic box H/ACA RNPs.
Alu repetitive sequences are the most abundant short interspersed DNA elements in the human genome. Full-length Alu elements are… 
2011
2011
Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface.
2011
2011
Accelerated hematopoietic stem cell aging in a mouse model of dyskeratosis congenita responds to antioxidant treatment
Mutations in DKC1, encoding telomerase associated protein dyskerin, cause X‐linked dyskeratosis congenita (DC), a bone marrow (BM… 
2010
2010
Chromosomal and telomeric reprogramming following ES-somatic cell fusion
Chromosomal and telomeric reprogramming was assessed in intraspecies hybrids obtained by fusion of embryonic stem (ES) cells and… 
Highly Cited
2009
Highly Cited
2009
Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP.
Dyskeratosis congenita (DC) is an inherited disorder that implicates defects in the biology of telomeres, which are maintained by… 
2008
2008
Trypanosome Spliced-Leader-Associated RNA (SLA1) Localization and Implications for Spliced-Leader RNA Biogenesis
ABSTRACT Spliced-leader-associated RNA (SLA1) guides the pseudouridylation at position −12 (relative to the 5′ splice site) of… 
2007
2007
DKC1 is a direct and conserved transcriptional target of c-MYC.
2007
2007
Dynamic interactions within sub-complexes of the H/ACA pseudouridylation guide RNP
H/ACA RNP complexes change uridines to pseudouridines in target non-coding RNAs in eukaryotes and archaea. H/ACA RNPs are… 
2006
2006
Archaeal pre-mRNA splicing: a connection to hetero-oligomeric splicing endonuclease.
2003
2003
Gene expression dose-response changes in microarrays after exposure of human peripheral lung epithelial cells to nickel(II).
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