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DKC1 gene

Known as: H/ACA ribonucleoprotein complex subunit 4, NOPP140-ASSOCIATED PROTEIN, 57-KD, XAP101 
This gene is involved in both H/ACA small nucleolar RNA ribonucleoprotein assembly and telomerase stabilization and maintenance.
National Institutes of Health

Related topics

Related topics

6 relations
DKC1 protein, humanH/ACA Ribonucleoprotein Complex Subunit 4, humanLigand BindingRNA Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis
Telomerase is a ribonucleoprotein (RNP) complex that synthesizes telomere repeats in tissue progenitor cells and cancer cells… 
Highly Cited
2008
Highly Cited
2008
Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly
Highly Cited
2007
Highly Cited
2007
Protein Composition of Catalytically Active Human Telomerase from Immortal Cells
Telomerase is a ribonucleoprotein enzyme complex that adds 5′-TTAGGG-3′ repeats onto the ends of human chromosomes, providing a… 
Review
2005
Review
2005
The many facets of H/ACA ribonucleoproteins
The H/ACA ribonucleoproteins (RNPs) are known as one of the two major classes of small nucleolar RNPs. They predominantly guide… 
Highly Cited
2005
Highly Cited
2005
Telomerase RNA Mutated in Autosomal Dyskeratosis Congenita Reconstitutes a Weakly Active Telomerase Enzyme Defective in Telomere Elongation
Dyskeratosis congenita (DC) is a rare multi-system syndrome characterized by naildystrophy, abnormal skin pigmentation and… 
Highly Cited
2004
Highly Cited
2004
Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins
Mammalian H/ACA small nucleolar RNAs and telomerase RNA share common sequence and secondary structure motifs that form… 
Highly Cited
2001
Highly Cited
2001
Identification of novel DKC1 mutations in patients with dyskeratosis congenita: implications for pathophysiology and diagnosis
Abstract. Dyskeratosis congenita (DC) is characterised by the failure of those tissues that are rapidly dividing in the adult… 
Highly Cited
1999
Highly Cited
1999
Point Mutations in Yeast CBF5 Can Abolish In Vivo Pseudouridylation of rRNA
ABSTRACT In budding yeast (Saccharomyces cerevisiae), the majority of box H/ACA small nucleolar RNPs (snoRNPs) have been shown to… 
Highly Cited
1999
Highly Cited
1999
minifly, A Drosophila Gene Required for Ribosome Biogenesis
We report here the genetic, molecular, and functional characterization of the Drosophila melanogaster minifly (mfl) gene. Genetic… 
Highly Cited
1993
Highly Cited
1993
An essential yeast protein, CBF5p, binds in vitro to centromeres and microtubules
Yeast centromere DNA (CEN) affinity column chromatography has been used to purify several putative centromere and kinetochore… 
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