DEFB1 gene

Known as: DEFB-1, HBD1, beta defensin 1 
This gene is involved in mitigating host inflammatory defense mechanisms in response to microbial invasion.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Human β-defensins (hBD) are antimicrobial peptides that curb microbial activity. Although hBD's are primarily expressed by… (More)
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2010
2010
Genetics is an important component in the determination of individual susceptibility to caries and periodontal diseases. Since… (More)
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2010
2010
Periodontal diseases are complex inflammatory diseases and affect up to 20% of the worldwide population. An unbalanced reaction… (More)
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Highly Cited
2009
Highly Cited
2009
A key step in many chromatin-related processes is the recognition of histone post-translational modifications by effector modules… (More)
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Highly Cited
2007
Highly Cited
2007
To identify genes dysregulated in bipolar disorder (BD1), we carried out global gene expression profiling using whole-genome… (More)
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2007
2007
Food-borne pathogens are responsible for most cases of food poisoning in developed countries and are often associated with… (More)
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Highly Cited
2002
Highly Cited
2002
Beta defensins are small cationic antimicrobial peptides present in the respiratory system which have been proposed to be… (More)
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2000
2000
The goal of this study was to develop a primary culture model of differentiated murine tracheal epithelium. When grown on… (More)
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Highly Cited
1998
Highly Cited
1998
One component of host defense at mucosal surfaces appears to be epithelium-derived peptides with antimicrobial activity called… (More)
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1998
1998
Defensins and other antimicrobial peptides act in the innate host defense of epithelial surfaces. Human beta defensin 1 (hBD-1… (More)
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