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DEFB1 gene

Known as: DEFB-1, HBD1, beta defensin 1 
This gene is involved in mitigating host inflammatory defense mechanisms in response to microbial invasion.
National Institutes of Health

Papers overview

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2015
2015
BACKGROUND Single-nucleotide polymorphisms (SNPs) in immune genes have been associated with susceptibility to invasive mold… Expand
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Highly Cited
2011
Highly Cited
2011
Human β-defensins (hBD) are antimicrobial peptides that curb microbial activity. Although hBD's are primarily expressed by… Expand
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Highly Cited
2010
Highly Cited
2010
Genetics is an important component in the determination of individual susceptibility to caries and periodontal diseases. Since… Expand
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Highly Cited
2009
Highly Cited
2009
A key step in many chromatin-related processes is the recognition of histone post-translational modifications by effector modules… Expand
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Highly Cited
2007
Highly Cited
2007
To identify genes dysregulated in bipolar disorder (BD1), we carried out global gene expression profiling using whole-genome… Expand
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Highly Cited
2007
Highly Cited
2007
The BET (bromodomains and extra terminal domain) family proteins recognize acetylated chromatin through their bromodomain and act… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT Bacteria have evolved strategies to resist killing by antimicrobial peptides (APs), important effectors of innate… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Beta defensins are small cationic antimicrobial peptides present in the respiratory system which have been proposed to… Expand
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Highly Cited
1998
Highly Cited
1998
ABSTRACT One component of host defense at mucosal surfaces appears to be epithelium-derived peptides with antimicrobial activity… Expand
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Highly Cited
1998
Highly Cited
1998
Defensins and other antimicrobial peptides act in the innate host defense of epithelial surfaces. Human beta defensin 1 (hBD-1… Expand
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