DEFB1 wt Allele

Known as: HBD-1, DEFB-1, Defensin, Beta 1 wt Allele 
Human DEFB1 wild-type allele is located within 8p23.2-p23.1 and is approximately 7 kb in length. This allele, which encodes beta-defensin 1 protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
We hypothesize that circadian dysfunction could underlie, at least partially, the liability for bipolar 1 disorder (BD1). Our… (More)
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Highly Cited
2006
Highly Cited
2006
This study examined the ability of nine human defensins (HD) to protect against herpes simplex virus infection. Noncytotoxic… (More)
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Highly Cited
2005
Highly Cited
2005
Beta-defensins are small (3 to 5 kDa in size) secreted antimicrobial and antiviral proteins that are components of innate… (More)
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2005
2005
Immaturity of innate immunity contributes to the increased susceptibility of human neonates to infection. The lung is a major… (More)
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Highly Cited
2004
Highly Cited
2004
Human skin is able to mount a fast response against invading harmful bacteria through the rapid production of inducible peptide… (More)
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Highly Cited
2002
Highly Cited
2002
The three human beta-defensins, HBD1--3, are 33--47-residue, cationic antimicrobial proteins expressed by epithelial cells. All… (More)
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Review
2001
Review
2001
Since we live in a dirty environment, we have developed many host defenses to contend with microorganisms. The epithelial lining… (More)
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Highly Cited
1999
Highly Cited
1999
The intestinal epithelium forms a physical barrier to limit access of enteric microbes to the host and contributes to innate host… (More)
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Highly Cited
1998
Highly Cited
1998
We cloned a second human beta-defensin gene, HBD-2, and determined its gene structure and expression in inflamed tissue sections… (More)
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Highly Cited
1997
Highly Cited
1997
A human bronchial xenograft model was used to characterize the molecular basis for the previously described defect in bacterial… (More)
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