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DEFB1 protein, human

Known as: hBD-1 protein, human, Beta-Defensin 1, Beta Defensin 1 
Beta-defensin 1 (68 aa, ~7 kDa) is encoded by the human DEFB1 gene. This protein is involved in chemotaxis and has bactericidal activity.
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Human β-defensins (hBD) are antimicrobial peptides that curb microbial activity. Although hBD's are primarily expressed by… Expand
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2009
2009
The activities of defensins HBD-1, HBD-2, and HBD-3 and their C-terminal analogs Phd1, Phd2, and Phd3 against Candida albicans… Expand
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Highly Cited
2005
Highly Cited
2005
We report the development of a multiplex reverse transcription-polymerase chain reaction (RT-PCR) method for the definitive… Expand
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Highly Cited
2004
Highly Cited
2004
The innate immune system plays a critical role in the defense of areas exposed to microorganisms. There is an increasing body of… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND & AIMS LL-37/human cationic antimicrobial peptide 18 (hCAP18) is a human cathelicidin with broad-spectrum… Expand
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Highly Cited
2002
Highly Cited
2002
Pneumonia and systemic infection are common in premature infants. The antimicrobial peptides human beta-defensin 1 and 2 (hBD-1… Expand
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Highly Cited
2000
Highly Cited
2000
Human gingival epithelial cells (HGE) express two antimicrobial peptides of the beta-defensin family, human beta-defensin 1 (hBD… Expand
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Highly Cited
1999
Highly Cited
1999
The intestinal epithelium forms a physical barrier to limit access of enteric microbes to the host and contributes to innate host… Expand
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Highly Cited
1998
Highly Cited
1998
Previous studies have implicated the novel peptide antibiotic human beta-defensin 1 (hBD-1) in the pathogenesis of cystic… Expand
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Highly Cited
1993
Highly Cited
1993
From 1970 to 1985, 663 patients underwent curative resection of colon and rectal adenocarcinomas. All surgical specimens were… Expand
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