DEFB1 protein, human

Known as: hBD-1 protein, human, Beta-Defensin 1, Beta Defensin 1 
Beta-defensin 1 (68 aa, ~7 kDa) is encoded by the human DEFB1 gene. This protein is involved in chemotaxis and has bactericidal activity.
National Institutes of Health

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Topic mentions per year

1986-2017
051019862017

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2004
2004
In this study we show a significant correlation between a single-nucleotide polymorphism in the 5'-untranslated region of the… (More)
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Highly Cited
2002
Highly Cited
2002
Beta defensins are small cationic antimicrobial peptides present in the respiratory system which have been proposed to be… (More)
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Highly Cited
2002
Highly Cited
2002
Pneumonia and systemic infection are common in premature infants. The antimicrobial peptides human beta-defensin 1 and 2 (hBD-1… (More)
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Highly Cited
2002
Highly Cited
2002
Human beta-defensins are broad-spectrum antimicrobial peptides known to be produced by epithelial cells. It was recently shown… (More)
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2001
Highly Cited
2001
The stratified epithelia of the oral cavity are continually exposed to bacterial challenge that is initially resisted by innate… (More)
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Highly Cited
2000
Highly Cited
2000
Human gingival epithelial cells (HGE) express two antimicrobial peptides of the beta-defensin family, human beta-defensin 1 (hBD… (More)
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Highly Cited
1999
Highly Cited
1999
beta-Defensins are cationic peptides with broad-spectrum antimicrobial activity that are produced by epithelia at mucosal… (More)
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1998
Highly Cited
1998
Previous studies have implicated the novel peptide antibiotic human beta-defensin 1 (hBD-1) in the pathogenesis of cystic… (More)
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Highly Cited
1998
Highly Cited
1998
Human beta-defensin-1 (hBD-1) is a member of the family of small cationic antimicrobial peptides that have been identified in… (More)
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Highly Cited
1993
Highly Cited
1993
From 1970 to 1985, 663 patients underwent curative resection of colon and rectal adenocarcinomas. All surgical specimens were… (More)
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