DDX58 gene

Known as: retinoic acid inducible gene I, DKFZp434J1111, RIG-I 
This gene plays a role in the antiviral response.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
MDA5, a viral double-stranded RNA (dsRNA) receptor, shares sequence similarity and signaling pathways with RIG-I yet plays… (More)
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Highly Cited
2012
Highly Cited
2012
Influenza A viruses can adapt to new host species, leading to the emergence of novel pathogenic strains. There is evidence that… (More)
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Highly Cited
2009
Highly Cited
2009
The innate immune system senses nucleic acids by germline-encoded pattern recognition receptors. RNA is sensed by Toll-like… (More)
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Highly Cited
2009
Highly Cited
2009
Upon recognition of viral components by pattern recognition receptors, including TLRs and retinoic acid-inducible gene I (RIG-I… (More)
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Highly Cited
2008
Highly Cited
2008
RIG-I senses intracellular virus-specific nucleic acid structures and initiates an antiviral response that induces interferon… (More)
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Highly Cited
2007
Highly Cited
2007
Retinoic-acid-inducible gene-I (RIG-I; also called DDX58) is a cytosolic viral RNA receptor that interacts with MAVS (also called… (More)
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Highly Cited
2007
Highly Cited
2007
Influenza A virus (IAV) triggers a contagious acute respiratory disease that causes considerable mortality annually. Recently, we… (More)
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Highly Cited
2006
Highly Cited
2006
Epstein-Barr virus (EBV)-encoded small RNAs (EBERs) are nonpolyadenylated, untranslated RNAs, exist most abundantly in latently… (More)
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Highly Cited
2005
Highly Cited
2005
Antiviral immunity against a pathogen is mounted upon recognition by the host of virally associated structures. One of these… (More)
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Highly Cited
2005
Highly Cited
2005
Toll-like receptors (TLRs) play an important role in antiviral response by recognizing viral components. Recently, a RNA helicase… (More)
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