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MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin.
MicroRNAs (miRNAs) may function as oncogenes or tumor suppressors. Here, we show that miR-27a is up-regulated in human gastric adenocarcinoma. Suppression of miR-27a inhibits gastric cancer cellExpand
MicroRNA‐9 inhibits ovarian cancer cell growth through regulation of NF‐κB1
MicroRNAs are emerging as important regulators of cancer‐related processes. Our studies show that microRNA‐9 (miR‐9) is downregulated in human ovarian cancer relative to normal ovary, andExpand
miR-490-3p Modulates Cell Growth and Epithelial to Mesenchymal Transition of Hepatocellular Carcinoma Cells by Targeting Endoplasmic Reticulum-Golgi Intermediate Compartment Protein 3 (ERGIC3)*
Background: The role of miR-490-3p in hepatocellular carcinoma (HCC) has not been well clarified. Results: miR-490-3p is up-regulated in HCC and enhances the cell proliferation, migration, invasionExpand
Plexin-B1 is a target of miR-214 in cervical cancer and promotes the growth and invasion of HeLa cells.
  • R. Qiang, F. Wang, +8 authors Hua Tang
  • Biology, Medicine
  • The international journal of biochemistry & cell…
  • 1 April 2011
Plexin-B1, the receptor for Sema4D, has been reported to trigger multiple and sometimes opposing cellular responses in various types of tumor cells. It has been implicated in the regulation ofExpand
Suppression of hepatitis B virus replication by microRNA-199a-3p and microRNA-210.
Accumulating evidence suggests that microRNAs (miRNAs) control the replication of both RNA and DNA viruses. In order to determine whether host-encoded miRNAs affect hepatitis B virus (HBV)Expand
MicroRNA‐214 is aberrantly expressed in cervical cancers and inhibits the growth of HeLa cells
MicroRNAs are a group of endogenously expressed, single‐stranded, 18–24 nt RNAs that regulate diverse cellular pathways. Although documented evidence indicates that some microRNAs can function asExpand
MicroRNA‐10a is involved in the metastatic process by regulating Eph tyrosine kinase receptor A4‐Mediated epithelial‐mesenchymal transition and adhesion in hepatoma cells *
MicroRNAs (miRNAs) have been reported to be associated with the development of cancers. However, the function of miRNAs in human hepatocellular carcinoma (HCC) remains largely undefined. Here weExpand
MiR‐214 reduces cell survival and enhances cisplatin‐induced cytotoxicity via down‐regulation of Bcl2l2 in cervical cancer cells
MiR‐214 has been shown to inhibit cell growth, migration and invasion. Here we demonstrate that ectopic expression of miR‐214 reduces cell survival, induces apoptosis and enhances sensitivity toExpand
Glycyrrhetinic acid-modified chitosan/poly(ethylene glycol) nanoparticles for liver-targeted delivery.
A liver-targeted drug delivery carrier, composed of chitosan/poly(ethylene glycol)-glycyrrhetinic acid (CTS/PEG-GA) nanoparticles, was prepared by an ionic gelation process, in which glycyrrhetinicExpand
Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma
MicroRNAs are short regulatory RNAs that negatively modulate gene expression at the post-transcriptional level, and are deeply involved in the pathogenesis of several types of cancers. To investigateExpand