DDIT4 wt Allele

Known as: RTP801, REDD-1, FLJ20500 
Human DDIT4 wild-type allele is located in the vicinity of 10q22.1 and is approximately 2 kb in length. This allele, which encodes DNA damage… (More)
National Institutes of Health

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Topic mentions per year

1996-2018
0102019962018

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Highly Cited
2011
Highly Cited
2011
Metformin is a widely prescribed antidiabetic drug associated with a reduced risk of cancer. Many studies show that metformin… (More)
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Highly Cited
2011
Highly Cited
2011
MicroRNAs (miRNAs) are involved in tumorigenecity by regulating specific oncogenes and tumor suppressor genes, and their roles in… (More)
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Highly Cited
2008
Highly Cited
2008
Hypoxia induces rapid and dramatic changes in cellular metabolism, in part through inhibition of target of rapamycin (TOR) kinase… (More)
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Highly Cited
2008
Highly Cited
2008
INTRODUCTION Blood flow restriction in combination with low-intensity resistance exercise (REFR) increases skeletal muscle size… (More)
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2008
2008
mTORC1 is a complex of proteins that includes the mammalian target of rapamycin (mTOR) and several regulatory proteins. It is… (More)
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Highly Cited
2006
Highly Cited
2006
The mammalian target of rapamycin (mTOR), a critical modulator of cell growth, acts to integrate signals from hormones, nutrients… (More)
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Highly Cited
2005
Highly Cited
2005
The tuberous sclerosis tumor suppressors TSC1 and TSC2 regulate the mTOR pathway to control translation and cell growth in… (More)
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Highly Cited
2004
Highly Cited
2004
Mammalian target of rapamycin (mTOR) is a central regulator of protein synthesis whose activity is modulated by a variety of… (More)
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Highly Cited
2002
Highly Cited
2002
We identified REDD1 as a novel transcriptional target of p53 induced following DNA damage. During embryogenesis, REDD1 expression… (More)
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1998
1998
Kss1, a yeast mitogen-activated protein kinase (MAPK), in its unphosphorylated (unactivated) state binds directly to and… (More)
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