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DB-67

Known as: DB 67, Silatecan AR-67, AR-67 
A synthetic, highly lipophilic derivative of camptothecin, with potential antineoplastic and radiosensitizing activities. 7-tert-butyldimethylsilyl… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

7-tert-butyldimethylsilyl-10-hydroxycamptothecin
DNA Replication InhibitionDNA Strand BreakTOP1 protein, human

Papers overview

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2013
2013
The Critical Role of Mechanism-Based Models for Understanding and Predicting Liposomal Drug Loading, Binding and Release Kinetics
OF DISSERTATION THE CRITICAL ROLE OF MECHANISM-BASED MODELS FOR UNDERSTANDING AND PREDICTING LIPOSOMAL DRUG LOADING, BINDING AND… 
2013
2013
The effect of BCRP , MDR 1 and OATP 1 B 3 on the antitumor efficacy of the lipophilic camptothecin AR-67 in vitro
2010
2010
Factors Affecting the In Vivo Lactone Stability and Systemic Clearance of the Lipophilic Camptothecin Analogue AR-67
ABSTRACTPurposeThe narrow efficacy-toxicity window of anticancer agents necessitates understanding of factors contributing to…