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DAPK1 gene

Known as: death associated protein kinase 1, DAPK, Death-Associated Protein Kinase 1 Gene 
This gene is involved in pro-apoptotic regulation.
National Institutes of Health

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Related topics

8 relations
DAPK1 protein, humanPhosphorylationPositive Regulation of ApoptosisSerine/Threonine Phosphorylation

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DAPK1 wt Allele

Papers overview

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Review
2013
Review
2013
Epigenetic modifications of DAPK and p16 genes contribute to arsenic-induced skin lesions and nondermatological health effects.
Over 26 million people in West Bengal, India, are exposed to very high levels of arsenic through drinking water, leading to… 
Review
2009
Review
2009
Interest of methylated genes as biomarkers in urothelial cell carcinomas of the urinary tract
Urothelial cell carcinomas (UCC), including bladder cancer and upper urinary tract cancer, are the second most common malignancy… 
Highly Cited
2008
Highly Cited
2008
Promoter Hypermethylation in Tumour Suppressor Genes Shows Association with Stage, Grade and Invasiveness of Bladder Cancer
Aims: Superficial bladder cancer is a highly recurrent disease, with progression to muscle invasiveness occurring in 15–30% of… 
Highly Cited
2007
Highly Cited
2007
Regulation of Death-associated Protein Kinase
Death-associated protein kinase (DAPK) has been found associated with HSP90, and inhibition of HSP90 with 17-alkylamino-17… 
Highly Cited
2006
Highly Cited
2006
DNA methyltransferases messenger RNA expression and aberrant methylation of CpG islands in non-small-cell lung cancer: association and prognostic value.
BACKGROUND A significant association between aberrant methylation in regulatory regions of tumor suppressor genes and clinical… 
Highly Cited
2005
Highly Cited
2005
Promoter hypermethylation of p16INK4a, E-cadherin, O6-MGMT, DAPK and FHIT in adenocarcinomas of the esophagus, esophagogastric junction and proximal stomach.
Although the incidence of Barrett's carcinomas (BC) and proximal gastric adenocarcinomas (PGC) is increasing, little is known… 
Highly Cited
2003
Highly Cited
2003
Promoter hypermethylation of multiple genes in astrocytic gliomas.
Promoter hypermethylation represents a primary mechanism in the inactivation of tumor suppressor genes during tumorigenesis. To… 
Highly Cited
2003
Highly Cited
2003
Epigenetic down-regulation of death-associated protein kinase in lung cancers.
Highly Cited
2003
Highly Cited
2003
Death-associated protein kinase promoter hypermethylation in normal human lymphocytes.
A high frequency of death-associated protein kinase (DAPK) promoter hypermethylation has been noted in B-cell malignancies, head… 
Highly Cited
1995
Highly Cited
1995
Assignment of DAP1 and DAPK--genes that positively mediate programmed cell death triggered by IFN-gamma--to chromosome regions 5p12.2 and 9q34.1, respectively.
DAP-kinase (DAPK) and DAP1 were recently identified as positive mediators of IFN-{gamma}-induced programmed cell death. The… 
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