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Cytochrome P450 Family 46

Known as: Cytochrome P-450 CYP46, Cytochrome P450 Family 46 [Chemical/Ingredient], Cytochrome P 450 CYP46 
A cytochrome P450 enzyme family that includes CHOLESTEROL 24-HYDROXYLASE, which is expressed primarily in the brain and functions in CHOLESTEROL… 
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Cholesterol is an essential component for neuronal physiology not only during development stage but also in the adult life… 
Review
2012
Review
2012
Highly Cited
2003
Highly Cited
2003
BACKGROUND CYP46, the gene encoding cholesterol 24-hydroxylase, plays a key role in the hydroxylation of cholesterol and thereby… 
Highly Cited
2002
Highly Cited
2002
Highly Cited
2002
Highly Cited
2002
Cholesterol and 24S-hydroxycholesterol are involved in the pathogenesis of Alzheimer's disease (AD). Increased serum cholesterol… 
Highly Cited
2001
Highly Cited
2001
The major cholesterol oxidation products in the human circulation are 27-hydroxycholesterol, 24-hydroxycholesterol, and 7alpha… 
Review
2000
Review
2000
Members of the nuclear-receptor superfamily mediate crucial physiological functions by regulating the synthesis of their target… 
Highly Cited
1999
Highly Cited
1999
The turnover of cholesterol in the brain is thought to occur via conversion of excess cholesterol into 24S-hydroxycholesterol, an…