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CYP46A1 gene

Known as: CYTOCHROME P450, FAMILY 46, SUBFAMILY A, POLYPEPTIDE 1, CYP46A1, CYTOCHROME P450, SUBFAMILY 46 
National Institutes of Health

Related topics

Related topics

3 relations
Cytochrome P450 46A1Cytochrome P450 Family 46cholesterol 24-hydroxylase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
LincRNA Plays a Role in the Effect of CYP46A1 Polymorphism in Alzheimer’s Disease – Related Pathology
Polymorphism of the cholesterol-24S-hydroxylase (CYP46A1) gene is thought to be a risk factor for Alzheimer’s disease (AD). A… 
2018
2018
Brain of the blind: transcriptomics of the golden-line cavefish brain
Abstract The genus Sinocyclocheilus (golden-line barbel) includes 25 species of cave-dwelling blind fish (cavefish) and more than… 
2017
2017
The relationship between Multidrug Resistance Protein 1(rs1045642) and Cholesterol 24-hydroxylase (rs754203) genes polymorphism with type 2 diabetes mellitus
Abstract Background: The involvement of genetic factors like gene polymorphisms has been found to contribute significantly to the… 
2016
2016
High Cholesterol Diet Increases Expression of Cholesterol 24-Hydroxylase and BACE1 in Rat Hippocampi: Implications for the Effect of Diet Cholesterol on Memory
Background: Abnormal cholesterol homeostasis is associated with the pathogenesis of neurodegenerative disease and cognitive… 
2012
2012
Neuronal differentiation alters the ratio of Sp transcription factors recruited to the CYP46A1 promoter
J. Neurochem. (2012) 120, 220–229. 
2012
2012
Single nucleotide polymorphism in the cholesterol-24S-hydroxylase (CYP46A1) gene and its association with CFH and LOC387715 gene polymorphisms in age-related macular degeneration.
PURPOSE We investigated the association of single nucleotide polymorphism (SNP) in the cholesterol-24S-hydroxylase (CYP46A1) gene… 
Review
2011
Review
2011
24S-hydroxycholesterol and cholesterol-24S-hydroxylase (CYP46A1) in the retina: from cholesterol homeostasis to pathophysiology of glaucoma.
2011
2011
Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination.
The major mechanism of brain cholesterol elimination is the conversion of cholesterol into 24S-hydroxycholesterol by CYP46A1, a… 
2010
2010
Sp proteins play a critical role in histone deacetylase inhibitor‐mediated derepression of CYP46A1 gene transcription
J. Neurochem. (2010) 113, 418–431. 
2009
2009
Combined use of mass spectrometry and heterologous expression for identification of membrane-interacting peptides in cytochrome P450 46A1 and NADPH-cytochrome P450 oxidoreductase.
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