• Publications
  • Influence
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
TLDR
There continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes, so it is important to update guidelines for monitoring autophagic activity in different organisms. Expand
Molecular and Therapeutic Potential and Toxicity of Valproic Acid
TLDR
An overview of the different clinical-trials involving VPA and its side effects encountered during treatment as well as its molecular properties are given. Expand
The Role of Cyclooxygenase-2 in Cell Proliferation and Cell Death in Human Malignancies
TLDR
The findings prompt us to analyze here the effects of a combination of COX-2 inhibitors together with different clinically used therapeutic strategies in order to further improve the efficiency of future anticancer treatments. Expand
Chemopreventive and therapeutic effects of curcumin.
TLDR
Curcumin is described as an anti-tumoral, anti-oxidant and anti-inflammatory agent capable of inducing apoptosis in numerous cellular systems capable of suppression, retardation or inversion of carcinogenesis. Expand
Histone deacetylase 6 in health and disease.
TLDR
Structural features of this histone deacetylase, regulation of its expression and activity, biological functions, implication in human disease initiation and progression, and novel and selective HDAC6 inhibitors are discussed. Expand
Melatonin: a pleiotropic molecule regulating inflammation.
TLDR
The interesting timing of pro- and anti-inflammatory effects, such as those affecting lipoxygenase activity, suggests that melatonin might promote early phases of inflammation on one hand and contribute to its attenuation on the other hand, in order to avoid complications of chronic inflammation. Expand
Dietary chalcones with chemopreventive and chemotherapeutic potential
TLDR
The inhibitory effects of these compounds on the different steps of carcinogenesis that reveal interesting chemopreventive and chemotherapeutic potential will be discussed. Expand
An Introduction to the Molecular Mechanisms of Apoptosis
TLDR
Investigating the mechanisms of apoptosis is important to discover new cellular regulators that could be potential targets for new death‐inducing drugs. Expand
A beginner's guide to NF-kappaB signaling pathways.
TLDR
Benefits that can issue from various studies on NF-kappaB are summarized, and a few compounds seem particularly promising. Expand
Chemopreventive potential of curcumin in prostate cancer
TLDR
Curcumin appears thus as a non-toxic alternative for prostate cancer prevention, treatment or co-treatment, consistent with this compound’s ability to up-induce pro-APoptotic proteins and to down-regulate the anti-apoptotic counterparts. Expand
...
1
2
3
4
5
...