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cholesterol 24-hydroxylase

Known as: Cholesterol 24 Hydroxylase, Brain Specific 24S Hydroxylase, Brain-Specific 24S-Hydroxylase 
A steroid hydroxylase that functions in CHOLESTEROL homeostasis in the brain. It converts cholesterol into 24S-hydroxycholesterol, which is… 
National Institutes of Health

Related topics

Related topics

12 relations
CYP46A1 geneIn BloodProcess of secretionantagonists & inhibitors

Narrower (2)

Cholestane Tetrol 24-HydroxylaseCytochrome P450 46A1

Broader (1)

Cytochrome P450 Family 46

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Evaluation of pharmacodynamic effects of cholesterol 24-hydroxylase inhibitor TAK-935 and its target engagement in animals (P5.263)
Objective: To characterize the pharmacodynamic effects of a cholesterol 24-hydroxylase (CH24H) inhibitor TAK-935 and demonstrate… 
2017
2017
The relationship between Multidrug Resistance Protein 1(rs1045642) and Cholesterol 24-hydroxylase (rs754203) genes polymorphism with type 2 diabetes mellitus
Abstract Background: The involvement of genetic factors like gene polymorphisms has been found to contribute significantly to the… 
2015
2015
title : Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology First
1. Author groups: Please check that all names have been spelled correctly and appear in the correct order. Please also check that… 
2014
2014
H63D mutation in hemochromatosis alters cholesterol metabolism and induces memory impairment
2013
2013
Stimulation of cerebral cholesterol turnover 1 Pharmacologic stimulation of cytochrome P 450 46 A 1 and cerebral cholesterol turnover in mice
Cytochrome P450 46A1 (CYP46A1) is a brainspecific cholesterol 24-hydroxylase responsible for the majority of cholesterol… 
2007
2007
[Correlation of cholesterol 24-hydroxylase and ATP-binding cassette transporter A1 polymorphisms with Alzheimer's disease].
OBJECTIVE To investigate the association of the single nucleotide polymorphisms (SNPs) A-->G in the intron 2 of cholesterol 24… 
Highly Cited
2002
Highly Cited
2002
Genetic variation in the cholesterol 24-hydroxylase (CYP46) gene and the risk of Alzheimer's disease
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