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Cyclic GMP
Known as:
guanosine 3'5' monophosphate
, Guanosine Cyclic-3',5'-Monophosphate
, 3',5'-Monophosphate, Guanosine Cyclic
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Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the…
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National Institutes of Health
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Related topics
Related topics
24 relations
Narrower (8)
8-(2-carboxymethylthio)-cGMP
8-(5-thioacetamidofluorescein)cyclic-GMP
8-bromocyclic GMP
8-nitroguanosine 3',5'-cyclic monophosphate
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Broader (5)
Guanosine Monophosphate
Nucleotides
Nucleotides, Cyclic
Second Messenger Systems
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In Blood
Process of secretion
agonists
analogs & derivatives
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
Lijun Sun
,
Jiaxi Wu
,
Fenghe Du
,
Xiang Chen
,
Zhijian J. Chen
Science
2013
Corpus ID: 206546470
DNA Sensing Is a (c)GAS DNA is normally localized to the nucleus, and so its cytoplasmic localization sends off alarm bells to…
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Review
2013
Review
2013
Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger
U. Römling
,
Michael Y. Galperin
,
M. Gomelsky
Microbiology and Molecular Reviews
2013
Corpus ID: 39036101
SUMMARY Twenty-five years have passed since the discovery of cyclic dimeric (3′→5′) GMP (cyclic di-GMP or c-di-GMP). From the…
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Highly Cited
2013
Highly Cited
2013
Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
Jiaxi Wu
,
Lijun Sun
,
+4 authors
Zhijian J. Chen
Science
2013
Corpus ID: 206545156
DNA Sensing Is a (c)GAS DNA is normally localized to the nucleus, and so its cytoplasmic localization sends off alarm bells to…
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Highly Cited
2011
Highly Cited
2011
STING is a direct innate immune sensor of cyclic-di-GMP
Dara L Burdette
,
K. Monroe
,
+5 authors
R. Vance
Nature
2011
Corpus ID: 4394163
The innate immune system detects infection by using germline-encoded receptors that are specific for conserved microbial…
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Highly Cited
2008
Highly Cited
2008
Riboswitches in Eubacteria Sense the Second Messenger Cyclic Di-GMP
N. Sudarsan
,
E. R. Lee
,
+4 authors
R. Breaker
Science
2008
Corpus ID: 206513651
Cyclic di-guanosine monophosphate (di-GMP) is a circular RNA dinucleotide that functions as a second messenger in diverse species…
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Review
2000
Review
2000
Guanylyl cyclases and signaling by cyclic GMP.
K. Lucas
,
G. Pitari
,
+5 authors
S. Waldman
Pharmacological Reviews
2000
Corpus ID: 9088259
Guanylyl cyclases are a family of enzymes that catalyze the conversion of GTP to cGMP. The family comprises both membrane-bound…
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Review
2000
Review
2000
Autophagy as a regulated pathway of cellular degradation.
D. Klionsky
,
S. Emr
Science
2000
Corpus ID: 7919527
Macroautophagy is a dynamic process involving the rearrangement of subcellular membranes to sequester cytoplasm and organelles…
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Highly Cited
1998
Highly Cited
1998
Defense gene induction in tobacco by nitric oxide, cyclic GMP, and cyclic ADP-ribose.
J. Durner
,
D. Wendehenne
,
D. Klessig
Proceedings of the National Academy of Sciences…
1998
Corpus ID: 6297648
Reactive oxygen species are believed to perform multiple roles during plant defense responses to microbial attack, acting in the…
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Highly Cited
1996
Highly Cited
1996
Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction.
M. Boolell
,
M. J. Allen
,
+5 authors
C. Gingell
International journal of impotence research
1996
Corpus ID: 26355489
Sildenafil (Viagra, UK-92,480) is a novel oral agent under development for the treatment of penile erectile dysfunction. Erection…
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Highly Cited
1985
Highly Cited
1985
Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment
E. E. Fesenko
,
S. S. Kolesnikov
,
A. L. Lyubarsky
Nature
1985
Corpus ID: 4315094
Vertebrate rod photoreceptors hyperpolarize when illuminated, due to the closing of cation-selective channels in the plasma…
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