Cyclic GMP

Known as: guanosine 3'5' monophosphate, Guanosine Cyclic-3',5'-Monophosphate, 3',5'-Monophosphate, Guanosine Cyclic 
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the… (More)
National Institutes of Health

Related topics

Related topics

24 relations

Narrower (8)

8-(2-carboxymethylthio)-cGMP8-(5-thioacetamidofluorescein)cyclic-GMP8-bromocyclic GMP8-nitroguanosine 3',5'-cyclic monophosphate
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Broader (5)

Guanosine MonophosphateNucleotidesNucleotides, CyclicSecond Messenger Systems
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In BloodProcess of secretionagonistsanalogs & derivatives
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Papers overview

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Highly Cited
2013
Highly Cited
2013
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
The presence of DNA in the cytoplasm of mammalian cells is a danger signal that triggers host immune responses such as the… (More)
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Highly Cited
2013
Highly Cited
2013
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Cytosolic DNA induces type I interferons and other cytokines that are important for antimicrobial defense but can also result in… (More)
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Highly Cited
2011
Highly Cited
2011
STING is a direct innate immune sensor of cyclic-di-GMP
The innate immune system detects infection by using germline-encoded receptors that are specific for conserved microbial… (More)
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Highly Cited
2005
Highly Cited
2005
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
Sustained cardiac pressure overload induces hypertrophy and pathological remodeling, frequently leading to heart failure… (More)
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Review
2003
Review
2003
Cyclic GMP phosphodiesterases and regulation of smooth muscle function.
Cyclic GMP (cGMP) made in response to atrial natriuretic peptide (ANP) or nitric oxide (NO) is an important regulator of short… (More)
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Highly Cited
1998
Highly Cited
1998
Defense gene induction in tobacco by nitric oxide, cyclic GMP, and cyclic ADP-ribose.
Reactive oxygen species are believed to perform multiple roles during plant defense responses to microbial attack, acting in the… (More)
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Highly Cited
1996
Highly Cited
1996
Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction.
Sildenafil (Viagra, UK-92,480) is a novel oral agent under development for the treatment of penile erectile dysfunction. Erection… (More)
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Highly Cited
1994
Highly Cited
1994
Cyclic GMP and calcium mediate phytochrome phototransduction
We have previously used single-cell assays in a phytochrome-deficient tomato mutant to demonstrate that phytochrome signaling… (More)
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Review
1993
Review
1993
Intracellular cyclic GMP receptor proteins.
Cyclic GMP is recognized as an important intracellular mediator of extracellular signals such as nitric oxide and natriuretic… (More)
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Review
1986
Review
1986
Cyclic GMP cascade of vision.
Cyclic GMP is central to visual excitation in vertebrate retinal rod cells. Sodium channels in the plasma membrane of the outer… (More)
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