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Cyclic GMP

Known as: guanosine 3'5' monophosphate, Guanosine Cyclic-3',5'-Monophosphate, 3',5'-Monophosphate, Guanosine Cyclic 
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the… Expand
National Institutes of Health

Related topics

Related topics

24 relations

Narrower (8)

8-(2-carboxymethylthio)-cGMP8-(5-thioacetamidofluorescein)cyclic-GMP8-bromocyclic GMP8-nitroguanosine 3',5'-cyclic monophosphate
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Broader (5)

Guanosine MonophosphateNucleotidesNucleotides, CyclicSecond Messenger Systems
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In BloodProcess of secretionagonistsanalogs & derivatives
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
DNA Sensing Is a (c)GAS DNA is normally localized to the nucleus, and so its cytoplasmic localization sends off alarm bells to… Expand
Review
2013
Review
2013
Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger
SUMMARY Twenty-five years have passed since the discovery of cyclic dimeric (3′→5′) GMP (cyclic di-GMP or c-di-GMP). From the… Expand
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Highly Cited
2011
Highly Cited
2011
STING is a direct innate immune sensor of cyclic-di-GMP
The innate immune system detects infection by using germline-encoded receptors that are specific for conserved microbial… Expand
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Highly Cited
2008
Highly Cited
2008
Riboswitches in Eubacteria Sense the Second Messenger Cyclic Di-GMP
Cyclic di-guanosine monophosphate (di-GMP) is a circular RNA dinucleotide that functions as a second messenger in diverse species… Expand
Highly Cited
2005
Highly Cited
2005
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
Sustained cardiac pressure overload induces hypertrophy and pathological remodeling, frequently leading to heart failure… Expand
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Review
2000
Review
2000
Guanylyl cyclases and signaling by cyclic GMP.
Guanylyl cyclases are a family of enzymes that catalyze the conversion of GTP to cGMP. The family comprises both membrane-bound… Expand
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Review
2000
Review
2000
Autophagy as a regulated pathway of cellular degradation.
Macroautophagy is a dynamic process involving the rearrangement of subcellular membranes to sequester cytoplasm and organelles… Expand
Highly Cited
1998
Highly Cited
1998
Defense gene induction in tobacco by nitric oxide, cyclic GMP, and cyclic ADP-ribose.
Reactive oxygen species are believed to perform multiple roles during plant defense responses to microbial attack, acting in the… Expand
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Highly Cited
1996
Highly Cited
1996
Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction.
Sildenafil (Viagra, UK-92,480) is a novel oral agent under development for the treatment of penile erectile dysfunction. Erection… Expand
Highly Cited
1985
Highly Cited
1985
Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment
Vertebrate rod photoreceptors hyperpolarize when illuminated, due to the closing of cation-selective channels in the plasma… Expand
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