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Complement C5a

Known as: Complement 5a, Complement Component 5a, Component 5a, Complement 
The minor fragment formed when C5 convertase cleaves C5 into C5a and COMPLEMENT C5B. C5a is a 74-amino-acid glycopeptide with a carboxy-terminal… 
National Institutes of Health

Related topics

Related topics

13 relations
C5 geneC5AR1 geneComplement C5a measurementComplement C5a:MCnc:Pt:Plas:Qn

Narrower (1)

C5aRAD

Broader (1)

Immunologic Factors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1986
1986
Comparative structural anatomy of the complement anaphylatoxin proteins C3a, C4a and C5a.
The anaphylatoxins are a family of proteins produced during the course of complement activation as the result of cleavage by… 
1986
1986
Enhancement of human polymorphonuclear leukocyte adherence to plastic and endothelium by phorbol myristate acetate. Comparison with human C5a.
The adherence of circulating neutrophils to vascular endothelium represents a necessary step in the chemotactic emigration of… 
Highly Cited
1985
Highly Cited
1985
Human C5a modulates monocyte Fc and C3 receptor expression.
FcIgG and C3 (CR1 and CR3) receptors are responsible for binding opsonized particles, phagocytosis, and immune adherence… 
1983
1983
Direct effect of complement factor C5a on the contractile state of isolated smooth muscle cells.
The complement-(C) derived factor C5a has long been recognized as a potent contractile agonist in smooth muscle (1,2); however… 
1982
1982
Potentiation of the primary humoral immune response in vitro by C5a anaphylatoxin.
The effect of the anaphylatoxin C5a on the primary humoral immune response to SRBC was studied in culture of spleen cells from… 
1981
1981
Enhancement of the chemotactic activity of human C5a des Arg by an anionic polypeptide ("cochemotaxin") in normal serum and plasma.
The potent chemoattractant, C5a is converted rapidly to C5a des Arg by a carboxypeptidase-like enzyme in normal human serum and… 
1980
1980
Mediators of immune complex-induced aggregation of polymorphonuclear neutrophils. I. C5a anaphylatoxin, neutrophil cationic proteins and their cleavage fragments.
This study reports the results of in vitro investigations on the aggregation of polymorphonuclear neutrophils (PMN) induced by… 
1980
1980
Aggregation of leukocytes induced by the complement-derived peptides C3a and C5a and by three synthetic formyl-methionyl peptides.
The highly purified hog complement peptides C3a and C5a and three formylmethionyl peptides induced dose-dependent aggregation of… 
1980
1980
Biological activities of C5a and C5adesArg from hog serum.
The complement-derived peptides C5a and C5adesArg (highly purified from yeast-activated hog serum) were both active in the… 
1979
1979
Enhancement of hexose uptake in human polymorphonuclear leukocytes by activated complement component C5a.
The polymorphonuclear leukocyte (PMNL) depends on glucose as a source of energy for motility, chemotaxis, phagocytosis, and… 
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