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C5AR1 gene

Known as: CD88, C5AR, COMPLEMENT COMPONENT 5a RECEPTOR 1 
National Institutes of Health

Related topics

Related topics

4 relations
C5 geneC5a anaphylatoxin receptorComplement C5aComplement C5a measurement

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Neuroprotective effects of argatroban and C5a receptor antagonist (PMX53) following intracerebral haemorrhage
Intracerebral haemorrhage (ICH) is a subtype of stroke that associated with neurological dysfunction and inflammation, which may… 
2014
2014
Urokinase receptor mediates osteogenic differentiation of mesenchymal stem cells and vascular calcification via the complement C5a receptor.
Vascular calcification is a severe consequence of several pathological processes with a lack of effective therapy. Recent studies… 
Highly Cited
2007
Highly Cited
2007
THE ROLE OF C5A IN THE INNATE IMMUNE RESPONSE AFTER EXPERIMENTAL BLUNT CHEST TRAUMA
The inflammatory response after severe blunt chest trauma often leads to acute lung injury and acute respiratory distress… 
Highly Cited
2004
Highly Cited
2004
Expression of a Functional C5a Receptor in Regenerating Hepatocytes and Its Involvement in a Proliferative Signaling Pathway in Rat1
Activation of the complement system generates the anaphylatoxin C5a whose activities are mediated through its binding to the… 
2000
2000
C5a modulation of interleukin-1 beta-induced interleukin-6 production by human osteoblast-like cells.
Periodontal bone resorption is controlled by osteoblast products, including interleukin (IL)-6, which are stimulated by other… 
Highly Cited
1999
Highly Cited
1999
Effects of a new C5a receptor antagonist on C5a‐ and endotoxin‐ induced neutropenia in the rat
A new C5a receptor antagonist, the cyclic peptide Phe‐[Orn‐Pro‐D‐cyclohexylalanine‐Trp‐Arg], (F‐[OPdChaWR]), was tested for its… 
Highly Cited
1998
Highly Cited
1998
Novel C5a receptor antagonists regulate neutrophil functions in vitro and in vivo.
Novel recombinant human C5a receptor antagonists were discovered through modification of the C terminus of C5a. The C5a1-71T1M… 
1998
1998
Cloning and characterization of the guinea pig C5a anaphylatoxin receptor: interspecies diversity among the C5a receptors.
The anaphylatoxin C5a receptor (C5aR, CD88 in man) plays a prominent role in mediating inflammatory and host defense processes… 
Highly Cited
1993
Highly Cited
1993
Anti-C5a receptor antibodies. Characterization of neutralizing antibodies specific for a peptide, C5aR-(9-29), derived from the predicted amino-terminal sequence of the human C5a receptor.
Results obtained indicate that a site-directed polyclonal antibody specific for a synthetic peptide based on the predicted amino… 
1980
1980
Decreased Phytohemagglutinin-Induced Aggregation and C5a-Induced Chemotaxis of Human Newborn Neutrophils
Summary: Phytohemagglutinin (PHA)-induced lectin aggregation, chemotactic response to C5a, and random migration were measured on… 
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