Skip to search formSkip to main contentSkip to account menu

C5AR1 gene

Known as: CD88, C5AR, COMPLEMENT COMPONENT 5a RECEPTOR 1 
National Institutes of Health

Related topics

Related topics

4 relations
C5 geneC5a anaphylatoxin receptorComplement C5aComplement C5a measurement

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
The C5a Receptor Impairs IL-12–Dependent Clearance of Porphyromonas gingivalis and Is Required for Induction of Periodontal Bone Loss
The C5a anaphylatoxin receptor (C5aR; CD88) is activated as part of the complement cascade and exerts important inflammatory… 
Highly Cited
2008
Highly Cited
2008
The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis1
Complement activation products are elevated in the cerebrospinal fluid and spinal cord of patients with amyotrophic lateral… 
Review
2008
Review
2008
Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2
Complement component C5a is one of the most potent inflammatory chemoattractants and has been implicated in the pathogenesis of… 
Highly Cited
2008
Highly Cited
2008
PROTECTIVE EFFECT OF C5A RECEPTOR INHIBITION AFTER MURINE REPERFUSED STROKE
OBJECTIVEThe complement cascade has been implicated in cerebral ischemia/reperfusion injury. To develop clinically useful… 
Highly Cited
2007
Highly Cited
2007
THE ROLE OF C5A IN THE INNATE IMMUNE RESPONSE AFTER EXPERIMENTAL BLUNT CHEST TRAUMA
The inflammatory response after severe blunt chest trauma often leads to acute lung injury and acute respiratory distress… 
Review
2004
Review
2004
Role of C5a–C5aR Interaction in Sepsis
C5a–C5aR signaling plays an essential role in innate immunity of neutrophils. However, excessive interaction of C5a–C5aR results… 
Highly Cited
2003
Highly Cited
2003
A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats.
BACKGROUND C5a has been implicated in numerous pathophysiological conditions, including ischemia/reperfusion (I/R) injury of the… 
Highly Cited
1996
Highly Cited
1996
Proteolytic inactivation of the leukocyte C5a receptor by proteinases derived from Porphyromonas gingivalis
The anaerobic bacterium Porphyromonas gingivalis has been implicated as a primary causative agent in adult periodontitis. Several… 
Highly Cited
1989
Highly Cited
1989
Endotoxin-induced shock in the rat. A role for C5a.
Administration of endotoxin from gram-negative bacteria to rats results in systemic hypotension, an increased hematocrit, and… 
Highly Cited
1985
Highly Cited
1985
Microvascular effects of anaphylatoxins C3a and C5a.
The direct microvascular effects of human C3a and C5a were investigated by using hamster cheek pouches prepared for intravital… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)