C5a anaphylatoxin receptor

Known as: CD88, Antigen, CD88, Receptors, C5a 
A G-protein-coupled receptor that signals an increase in intracellular calcium in response to the potent ANAPHYLATOXIN peptide COMPLEMENT C5A.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2018
0102019682018

Papers overview

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Highly Cited
2009
Highly Cited
2009
Anti-neutrophil cytoplasmic autoantibody (ANCA)-induced necrotizing crescentic glomerulonephritis (NCGN) requires complement… (More)
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Highly Cited
2008
Highly Cited
2008
The function of the C5a receptors, C5ar (encoded by C5ar) and C5l2 (encoded by Gpr77), especially of C5l2, which was originally… (More)
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Highly Cited
2007
Highly Cited
2007
Microarray expression profiles reveal substantial changes in gene expression in the ipsilateral dorsal horn of the spinal cord in… (More)
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Highly Cited
2003
Highly Cited
2003
Antiphospholipid syndrome (APS) is defined by recurrent pregnancy loss and thrombosis in the presence of antiphospholipid (aPL… (More)
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Highly Cited
2003
Highly Cited
2003
C5a anaphylatoxin, a potent inflammatory mediator, is known to act through a specific G protein coupled receptor. However, some… (More)
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Highly Cited
2002
Highly Cited
2002
The substantial variations in the responses of cells to the anaphylatoxin C5a and its desarginated form, C5adR(74), suggest that… (More)
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2002
2002
The anaphylatoxin, complement 5a (C5a), plays a key role in mediating various inflammatory reactions following complement… (More)
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1997
1997
Activation of the complement cascade plays an essential role in the early stages of inflammation. C5a and its receptor are… (More)
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Highly Cited
1995
Highly Cited
1995
The small-complement C5 activation fragment, C5a, is a potent phlogistic molecule that, on binding to the C5a Receptor (C5aR… (More)
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1995
1995
The C fragment C5a exerts its important physiologic and pathologic effects through interaction with a specific C5a receptor (C5aR… (More)
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